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Integrin alpha 8 beta 1

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Part of Bioactivity data

IT1-H52W9-ELISA
Human ITGA8&ITGB1 Heterodimer Protein, His Tag&Tag FreeHuman ITGA8&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52W9) ELISA bioactivity

Immobilized Human Fibronectin at 2 μg/mL (100 μL/well) can bind Human ITGA8&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52W9) with a linear range of 0.016-0.5 μg/mL (QC tested).

IT1-H82Wb-ELISA
Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His,Avitag&Tag FreeBiotinylated Human ITGA8&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT1-H82Wb) ELISA bioactivity

Immobilized Fibronectin at 5 μg/mL (100 μL/well) can bind Biotinylated Human ITGA8&ITGB1 Heterodimer Protein, His,Avitag&Tag Free (Cat. No. IT1-H82Wb) with a linear range of 0.156-5 μg/mL (QC tested).

Synonym Name

Integrin alpha 8 beta 1,ITGA8&ITGB1

Background

Human Integrin alpha 8 beta 1 Heterodimer Protein consists of ITGA8 and ITGB1. The integrin alpha 8 subunit, isolated by low stringency hybridization, is a novel integrin subunit that associates with beta 1. The recently identified alpha 8 integrin subunit associates with beta 1 and is predominantly expressed in smooth muscle and other contractile cells in adult tissues, and in mesenchymal and neural cells during development. In addition, Integrin alpha 8 beta 1 is a receptor for fibronectin and can promote attachment, cell spreading, and neurite outgrowth on fibronectin.

Clinical and Translational Updates

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