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Integrin alpha 11 beta 1

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Part of Bioactivity data

IT1-H52W3-SPR
Human ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag FreeHuman ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52W3) ELISA bioactivity

Immobilized Human Collagen I protein at 2 μg/mL (100 μL/well) can bind Human ITGA11&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52W3) with a linear range of 0.078-1.25 μg/mL (QC tested).

Synonym Name

Integrin alpha 11 beta 1,ITGA11&ITGB1

Background

Integrin alpha 11 beta 1 is a receptor for collagen. The alpha11 cDNA encodes a mature protein with a large 1120-residue extracellular domain that contains an I-domain of 207 residues and is linked by a transmembrane domain to a short cytoplasmic domain of 24 amino acids. The deduced alpha11 protein shows the typical structural features of integrin alpha-subunits and is similar to a distinct group of alpha-subunits from collagen-binding integrins.

Clinical and Translational Updates

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