SLC1A5
SLC1A5 Molecule Synonym Name
ASCT2, M7V1, RDR, RDRC, ATB(0), AAAT, ASCT2M7VS1, M7V1ATBO, R16, RD114, RDRCFLJ31068
SLC1A5 Molecule Background
Sodium-dependent amino acids transporter(SLC1A5) that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904).
SLC1A5 References
Kekuda R., et al. 1996, J Biol Chem., 271(31), 18657-61.
Blond JL., et al. 2000, J Virol., 74(7), 3321-9.
Sugimoto J., et al. 2017,Sci Rep., 3,1462.
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