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Your Position: Home > Integrin alpha 1 beta 1

Integrin alpha 1 beta 1

Brief Information

Name:Integrin alpha1/beta1
Target Synonym:Integrin alpha1beta1
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:1
Lastest Research Phase:Phase 2 Clinical

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Part of Bioactivity data

IT1-H52Wb-ELISA
Human ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag FreeHuman ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52Wb) ELISA bioactivity

Immobilized Human Collagen I protein at 2 μg/mL (100 μL/well) can bind Human ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52Wb) with a linear range of 1-20 ng/mL (QC tested).

IT1-M52W6-ELISA
Mouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag FreeMouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-M52W6) ELISA bioactivity

Immobilized Human Collagen IV at 2 μg/mL (100 μL/well) can bind Mouse ITGA1&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-M52W6) with a linear range of 10-78 ng/mL (QC tested).

Synonym Name

Integrin alpha 1 beta 1,ITGA1&ITGB1

Background

Integrin alpha-1/beta-1 is a receptor for laminin and collagen. The Integrin alpha-1/beta-1 and Integrin alpha-2/beta-1 integrins provide critical support for vascular endothelial growth factor signaling, endothelial cell migration, and tumor angiogenesis. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.

Clinical and Translational Updates

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
SAN-300 SAN-300 Phase 2 Clinical Biogen Inc Arthritis, Rheumatoid Details

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