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Your Position: Home > All Other Proteins > Transferrin R2 > TF2-M5269

Mouse Transferrin R2 Protein, mouse IgG1 Fc Tag, low endotoxin

  • Synonym
    Transferrin R2,TFR2
  • Source
    Mouse TFR2, Mouse Fc Tag (TF2-M5269) is expressed from human 293 cells (HEK293). It contains AA Arg 103 - Phe 798 (Accession # Q9JKX3).
    Predicted N-terminus: Val
  • Molecular Characterization
    Online(Arg 103 - Phe 798) Q9JKX3

    This protein carries a mouse IgG1 Fc tag at the N-terminus.

    The protein has a calculated MW of 101.1 kDa. The protein migrates as 116 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 0.1 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Mouse TFR2, Mouse Fc Tag (Cat. No. TF2-M5269) SDS-PAGE gel

Mouse TFR2, Mouse Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

  • Background
    Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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