Product Details
Synonyms
ROR1, NTRKR1
Source
Human / Cynomolgus / Rhesus macaque ROR1, Mouse IgG2a Fc Tag (RO1-H5256) is expressed from human 293 cells (HEK293). It contains AA Gln 30 - Glu 403 (Accession # Q01973-1). In the region Gln 30 - Glu 403, the amino acid sequences of Human, Cynomolgus and Rhesus macaque ROR1 are identical.
Predicted N-terminus: Gln 30
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a mouse IgG2a Fc tag at the C-terminus.
The protein has a calculated MW of 68.9 kDa. The protein migrates as 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 0.1 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Human / Cynomolgus / Rhesus macaque ROR1, Mouse IgG2a Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS

The purity of Human / Cynomolgus / Rhesus macaque ROR1, Mouse IgG2a Fc Tag (Cat. No. RO1-H5256) is more than 95% and the molecular weight of this protein is around 145-185 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Human / Cynomolgus / Rhesus macaque ROR1 Protein, Mouse IgG2a Fc Tag (Cat. No. RO1-H5256) at 1 μg/mL (100 μL/well) can bind Anti-ROR1 Antibody,Human IgG1 | Kappa with a linear range of 0.08-3 ng/mL (QC tested).
Protocol
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Background
Recent Advances
- English Name:
Inactive tyrosine-protein kinase transmembrane receptor ROR1
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
22 Details
- Highest Development Stage:
Phase 3 Clinical
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