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Your Position: Home > Protein > PLGF > PGF-H52G3

Human PlGF-1 Protein, GST Tag

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  • Synonym
    PGF,PLGF,PlGF,PGFL,SHGC-10760
  • Source
    Human PlGF-1 Protein, GST Tag(PGF-H52G3) is expressed from human 293 cells (HEK293). It contains AA Leu 19 - Arg 149 (Accession # P49763-2).
    Predicted N-terminus: Leu 19
  • Molecular Characterization
    PLGF Structure

    This protein carries a GST tag at the C-terminus.

    The protein has a calculated MW of 41.0 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
  • Clinical and Translational Updates

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Drug Development Status

  • Number of Launched Drugs:4 Details
  • Number of Drugs in Clinical Trials:15 Details
  • Latest Research Phase:Approved

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