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Your Position: Home > Protein > PADI2 > PA2-M5544

Mouse PADI2 Protein, His Tag (MALS verified)

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  • Synonym
    PADI2,PAD-H19,KIAA0994,PAD2,PDI2
  • Source
    Mouse PADI2, His Tag (PA2-M5544) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 673 (Accession # Q08642-1).
    Predicted N-terminus: Met
  • Molecular Characterization
    Online(Met 1 - Pro 673) Q08642-1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 78.3 kDa. The protein migrates as 66-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by reduced SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, 1 mM EDTA, 0.5 mM TCEP, pH7.4 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • Shipping
    This product is supplied and shipped with dry ice, please inquire the shipping cost.
SDS-PAGE
Mouse PADI2, His Tag (Cat. No. PA2-M5544) SDS-PAGE gel

Mouse PADI2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Mouse PADI2, His Tag (Cat. No. ) MALS images

The purity of Mouse PADI2, His Tag (Cat. No. PA2-M5544) is more than 85% and the molecular weight of this protein is around 140-171 kDa verified by SEC-MALS.

  • Background
    Protein-arginine deiminase type-2 (PADI2) are calcium-dependent histone-modifying enzymes whose activity is dysregulated in inflammatory diseases and cancer. This enzyme which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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