Product Details
Synonyms
Leucine-rich repeat-containing protein 15, LRRC15, LIB, hLib
Source
Biotinylated Cynomolgus / Rhesus macaque LRRC15, His,Avitag (LR5-C82E7) is expressed from human 293 cells (HEK293). It contains AA Tyr 22 - Gly 538 (Accession # A0A2K5UKB6-1). In the region Tyr 22 - Gly 538, the amino acid sequences of Cynomolgus and Rhesus macaque LRRC15 are identical.
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
The protein has a calculated MW of 61.6 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Labeling
Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
Protein Ratio
Passed as determined by the HABA assay / binding ELISA.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE

Biotinylated Cynomolgus / Rhesus macaque LRRC15, His,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS

The purity of Biotinylated Cynomolgus / Rhesus macaque LRRC15, His,Avitag (Cat. No. LR5-C82E7) is more than 85% and the molecular weight of this protein is around 80-115 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Biotinylated Cynomolgus / Rhesus macaque LRRC15, His,Avitag (Cat. No. LR5-C82E7) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Samrotamab with a linear range of 0.1-2 ng/mL (QC tested).
Protocol
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Background
Recent Advances
- English Name:
Leucine-rich repeat-containing protein 15
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
0 Details
- Highest Development Stage:
Preclinical
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