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Your Position: Home > Cytokines > IL-18 R beta > ILB-H5256

Human IL-18 R beta / IL-1 R7 Protein, Fc Tag

  • Synonym
    IL-18 R beta,IL-1 R7,CD218b,CDw218b,IL-1 R7,IL-18 R beta,IL-18 receptor accessory protein,IL-18 receptor beta,IL18R beta,IL-18RAcP
  • Source
    Human IL-18 R beta / IL-1 R7, Fc Tag (ILB-H5256) is expressed from human 293 cells (HEK293). It contains AA Phe 20 - Arg 356 (Accession # O95256-1).
    Predicted N-terminus: Phe 20
  • Molecular Characterization
    Online(Phe 20 - Arg 356) O95256-1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 64.9 kDa. The protein migrates as 70-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human IL-18 R beta / IL-1 R7, Fc Tag (Cat. No. ILB-H5256) SDS-PAGE gel

Human IL-18 R beta / IL-1 R7, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-SPR
Human_FcRn_Heterodimer_Protein_SPR

Biotinylated Human IL-18 R1, His,Avitag (Cat. No. IL1-H82E7) captured on Biotin CAP-Series S Sensor Chip can bind Human IL-18, Tag Free (Cat. No. IL8-H5113) (Premixed with Human IL-18 R beta / IL-1 R7, Fc Tag, Cat. No. ILB-H5256) with an affinity constant of 5.87 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

  • Background
    IL-18 R beta (IL-1R7), also known as IL18RAP (Interleukin 18 Receptor Accessory Protein), is a member of the IL-1 family. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-ka
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $198.00

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