Generally usable: Generally usable for removing all forms of DNA and RNA from biological products, reducing viscosity and preventing cell clumping.
Efficient: Efficient reaction, rapid degradation, reduce processing time.
Native: Native structure, tag free, the enzyme activity is more guaranteed.
Ideal: Ideal for DNA and RNA clearance
Ultra pure: Ultra pure: High purity and activity
Specific: Specific nuclease, no protease activity
Elimination of nucleic acids from recombinant proteins
Preclinical viral vaccine production, which will transit from preclinical development to clinical phases.
Preclinical viral vector production for cell and gene therapy（CGT）,which will transit from preclinical development to clinical phases.
Other preclinical development and production uses
<0.05ng/ug of protein tested by ELISA.
The sterility testing was performed by membrane filtration method.
>95% as determined by SDS-PAGE.
>99% as determined by SEC-HPLC.
Supplied as 0.2 μm filtered solution in 20mM Tris, 20mM NaCl, 2mM MgCl2, pH 8.0 with 50% Glycerol as protectant.
Avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -20°C or lower upon receipt;
-20°C for 24 months under sterile conditions.
GENIUS™ Nuclease, premium grade on SDS-PAGE under condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
The purity of GENIUS™ Nuclease, premium grade (Cat.No.NUE-S5119) was greater than 99% as determined by SEC-HPLC.
Specific activity for GENIUS™ Nuclease, premium grade is measured under standard assay conditions. The specific activity of GENIUS™ Nuclease, premium grade is >1.2 x 10e6 units/mg protein. One unit will digest sonicated salmon sperm DNA to acid-soluble oligonucleotides equivalent to a ΔA260 of 1.0 in 30 min at pH 8.0 at 37 °C, which corresponds approximately to complete digestion of 37 μg DNA. Note that 1 KU=1000 units.
GENIUS™ Nuclease, premium grade shows high specific activity.
The specific activity shows that GENIUS™ Nuclease, premium grade is stable at 4°C for 14 days.
The specific activity shows that GENIUS™ Nuclease, premium grade is stable at 37°C for 48 hours.
Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.
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