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Your Position: Home > ADC > TROP-2 > TR2-R52H9

Rabbit TROP-2 / TACSTD2 Protein, His Tag (MALS verified)

  • Synonym
    TACSTD2,GA733-1,M1S1,TROP2
  • Source
    Rabbit TROP-2, His Tag(TR2-R52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Pro 279 (Accession # G1T6B6-1 ).
    Predicted N-terminus: Gln 35
  • Molecular Characterization
    TROP-2 Structure

    This protein carries a polyhistidine tag at the C-terminus

    The protein has a calculated MW of 29.5 kDa. The protein migrates as 40-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
TROP-2 SDS-PAGE

Rabbit TROP-2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
TROP-2 MALS images

The purity of Rabbit TROP-2, His Tag (Cat. No. TR2-R52H9) is more than 90% and the molecular weight of this protein is around 32-42 kDa verified by SEC-MALS.

  • Background
    TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.
  • Clinical and Translational Updates
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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