Anti-CTLA-4 monoclonal antibody (Regeneron) |
REGN-4659 |
Phase 1 Clinical |
Regeneron Pharmaceuticals Inc |
Carcinoma, Non-Small-Cell Lung |
Details
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Recombinant anti-CTLA-4 human monoclonal antibody (Henlius) |
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Phase 1 Clinical |
Shanghai Henlius Biotech Co Ltd |
Carcinoma, Renal Cell; Colorectal Neoplasms; Melanoma |
Details
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B7-2/GM-CSF cancer gene therapy |
CIT |
Phase 1 Clinical |
Radient |
Neoplasms |
Details
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Anti-CTLA-4 and PD-1 CAR-T cell therapy (Shanghai Cell Therapy Research Institute) |
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Phase 2 Clinical |
Shanghai Cell Therapy Research Institute |
Neoplasms |
Details
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PD-L1/CTLA4 bispecific monoclonal antibody (Changhai Hospital) |
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Phase 2 Clinical |
Changhai Hospital Of Shanghai |
Pancreatic Neoplasms |
Details
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Anti-CTLA-4/PD-1 expressing EGFR-CAR-T |
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Phase 2 Clinical |
Shanghai Cell Therapy Research Institute |
Solid tumours |
Details
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SKB-337 |
SKB337; A-337; SKB-337 |
Phase 1 Clinical |
Sichuan Kelun-Biotech Biopharmaceutical Co Ltd |
Solid tumours |
Details
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Recombinant anti-CTLA-4 human monoclonal antibody (Hualan Biological Engineering) |
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Phase 2 Clinical |
Hualan Genetic Engineering Co Ltd |
Melanoma |
Details
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Ipilimumab biosimilar (Mab-Venture/ShuangLu Pharmaceutical) |
MV-049 |
Phase 1 Clinical |
Beijing Sl Pharmaceutical Co Ltd, Mab-Venture Biopharm Co Ltd |
Solid tumours |
Details
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Abatacept (Orban Biotech) |
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Phase 2 Clinical |
Orban Biotech, The National Institute Of Diabetes And Digestive And Kidney Diseases |
Diabetes Mellitus, Type 1 |
Details
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RIVAL-01 |
TBio-6517; TAK-605 |
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Takeda Pharmaceutical Co Ltd, Turnstone Biologics Inc |
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Details
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FPT-155 |
CD80-Fc; FPT-155 |
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Five Prime Therapeutics Inc |
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Details
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BAT-4706 |
BAT-4706 |
Phase 1 Clinical |
Bio-Thera Solutions Ltd |
Melanoma |
Details
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JS-007 |
JS-007 |
Phase 1 Clinical |
Shanghai Junshi Biosciences Co Ltd |
Solid tumours; Neoplasms; Lung Neoplasms; Melanoma |
Details
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CD-200-AR-L |
CD-200-AR-L; hP-1-A-8 |
Phase 1 Clinical |
University Of Minnesota |
Glioblastoma |
Details
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ADG-126 |
ADG-126 |
Phase 2 Clinical |
Adagene Inc |
Solid tumours |
Details
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RP-3 |
RP-3 |
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Replimune Inc |
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Details
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TWP-102 |
TWP-102 |
Phase 1 Clinical |
Therawisdom Biopharma Co Ltd |
Neoplasms |
Details
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XTX-101 |
XTX-101 |
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Details
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IMM-27M |
IMM27M; IMM-27M |
Phase 1 Clinical |
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Solid tumours |
Details
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ADG-116 |
ADG-116 |
Phase 2 Clinical |
Adagene (Suzhou) Ltd |
Solid tumours |
Details
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BMS-986249 |
BMS-986249 |
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Cytomx Therapeutics |
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Details
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HBM-4003 |
HBM-4003 |
Phase 2 Clinical |
Harbour Biomed |
Solid tumours; Neoplasms; Neuroendocrine Tumors; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Melanoma |
Details
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Ipilimumab biosimilar (Innovent Biologics) |
IBI-310 |
Phase 3 Clinical |
Innovent Biologics(Suzhou) Co Ltd |
Solid tumours; Liver Neoplasms; Nasopharyngeal Carcinoma; Colorectal Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular; Uterine Cervical Neoplasms |
Details
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BCD-217 |
BCD-217 |
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Biocad |
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Details
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Nurulimab |
BCD-145 |
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Biocad |
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Details
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Zalifrelimab |
AGEN-1884; RebmAb-600; UGN-301 |
Phase 1 Clinical |
4-Antibody, Ludwig Institute For Cancer Research |
Solid tumours; Urinary Bladder Neoplasms |
Details
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ADU-1604 |
ADU-1604 |
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Aduro Biotech |
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Details
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RP-2 |
RP-2 |
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Replimune, Bristol-Myers Squibb Company |
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Details
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ATOR-1015 |
ADC-1015; ATOR-1015 |
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Alligator Bioscience |
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Details
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Bavunalimab |
XmAb-22841; XmAb-841 |
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Xencor |
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Details
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ONCR-177 |
ONCR-177 |
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Oncorus |
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Details
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BA-3071 |
CAB-CTLA-4; BA-3071 |
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Beigene Ltd, Bioatla |
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Details
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Davoceticept |
ALPN-202 |
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Alpine Immune Sciences |
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Details
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Quavonlimab |
MK-1308; AK-107 |
Phase 2 Clinical |
Zhongshan Akeso Biopharma Co Ltd, Merck Sharp & Dohme Corp |
Solid tumours; Carcinoma, Renal Cell; Neoplasms; Small Cell Lung Carcinoma; Melanoma; Carcinoma, Non-Small-Cell Lung |
Details
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BT-001 |
BT-001 |
Phase 2 Clinical |
Transgene |
Solid tumours; Carcinoma, Merkel Cell; Neoplasms; Triple Negative Breast Neoplasms; Sarcoma; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung; Melanoma |
Details
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MEDI-5752 |
MEDI-5752 |
Phase 1 Clinical |
Medimmune Llc |
Solid tumours; Carcinoma, Renal Cell |
Details
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IO-102 |
IO-102 |
Phase 2 Clinical |
Herlev Hospital, Merck Sharp & Dohme Corp, Io Biotech |
Carcinoma; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Squamous Cell; Mouth Neoplasms; Carcinoma, Non-Small-Cell Lung |
Details
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YH-001 |
YH-001 |
Phase 2 Clinical |
Eucure Pharmaceutical Technology (Beijing) Co Ltd |
Solid tumours; Liver Neoplasms; Neoplasms; Sarcoma; Melanoma; Carcinoma, Non-Small-Cell Lung |
Details
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Vudalimab |
XmAb-20717; XmAb-717 |
Phase 2 Clinical |
Xencor |
Vulvar Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Melanoma; Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Thyroid Neoplasms; Fallopian Tube Neoplasms; Carcinoma, Neuroendocrine; Thymoma; Carcinoma, Squamous Cell; Astrocytoma; Colorectal Neoplasms; Adenocarcinoma, Clear Cell; Cholangiocarcinoma; Prostatic Neoplasms; Solid tumours; Breast Neoplasms; Nasopharyngeal Carcinoma; Adnexal Diseases; Mesothelioma; Adenoma, Acidophil; Carcinoma, Ovarian Epithelial; Small Cell Lung Carcinoma; Carcinoma, Transitional Cell; Carcinoma, Renal Cell; Stomach Neoplasms; Esophageal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Basal Cell; Ovarian Neoplasms; Biliary Tract Neoplasms |
Details
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Botensilimab |
AGEN-1181 |
Phase 1 Clinical |
Agenus Inc |
Ovarian Neoplasms; Solid tumours; Hemangiosarcoma; Neoplasms; Fibrolamellar hepatocellular carcinoma; Endometrial Neoplasms; Melanoma; Carcinoma, Non-Small-Cell Lung |
Details
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IDO-derived peptide vaccine/PD-L1-derived peptide vaccine |
IO-102/IO-103 |
Phase 3 Clinical |
Herlev Hospital |
Squamous Cell Carcinoma of Head and Neck; Melanoma |
Details
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Pembrolizumab/Quavonlimab |
MK-1308A |
Phase 3 Clinical |
Merck Sharp & Dohme Corp, Msd Ireland (Carlow), Moshadong R & D (China) Co Ltd |
Solid tumours; Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Colorectal Neoplasms; Carcinoma, Hepatocellular; Melanoma |
Details
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Erfonrilimab |
KN-046; KN046 |
Phase 3 Clinical |
Jiangsu Alphamab Biopharmaceuticals Co Ltd, Suzhou Alphamab Co Ltd |
Solid tumours; Liver Neoplasms; Esophageal Neoplasms; Stomach Neoplasms; Triple Negative Breast Neoplasms; Pancreatic Neoplasms; Breast Neoplasms; Thymus Neoplasms; Carcinoma, Pancreatic Ductal; Lymphoma; Thymoma; Carcinoma, Squamous Cell; Esophageal Squamous Cell Carcinoma; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular |
Details
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Lorigerlimab |
MGD-019; AEX1344 |
Phase 2 Clinical |
Macrogenics |
Liver Neoplasms; Solid tumours; Skin Melanoma; Carcinoma, Renal Cell; Carcinoma, Ovarian Epithelial; Neoplasms; Prostatic Neoplasms, Castration-Resistant; Prostatic Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Melanoma; Neoplasm Metastasis; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung |
Details
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CS-1002 |
SHR-8068; CS-1002 |
Phase 2 Clinical |
Cstone Pharmaceuticals |
Solid tumours; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular |
Details
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KN-044 |
KN-044 |
Phase 1 Clinical |
Suzhou Alphamab Co Ltd |
Solid tumours; Neoplasms |
Details
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ONC-392 |
ONC-392 |
Phase 2 Clinical |
Oncoimmune |
Carcinoma, Adenoid Cystic; Adenocarcinoma; Melanoma; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung; Fallopian Tube Neoplasms; Colorectal Neoplasms; Peritoneal Neoplasms; Breast Neoplasms; Sarcoma; Prostatic Neoplasms; Ovarian Neoplasms; Pancreatic Neoplasms; Carcinoma, Transitional Cell; Salivary Gland Neoplasms; Small Cell Lung Carcinoma; Carcinoma, Renal Cell; Esophageal Neoplasms; Cystadenocarcinoma, Serous; Stomach Neoplasms; Solid tumours; Head and Neck Neoplasms |
Details
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Iparomlimab/Tuvonralimab |
QL-1706; PSB-205; PBS-103/PBS-105 |
Phase 3 Clinical |
Qilu Pharmaceutical Co Ltd |
Liver Neoplasms; Solid tumours; Carcinoma, Renal Cell; Small Cell Lung Carcinoma; Neoplasms; Colorectal Neoplasms; Uterine Cervical Neoplasms; Carcinoma, Non-Small-Cell Lung |
Details
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SI-B003 |
SI-B003 |
Phase 1 Clinical |
Sichuan Baili Pharmaceutical Co Ltd |
Solid tumours; Stomach Neoplasms; Carcinoma, Renal Cell; Carcinoma, Transitional Cell; Triple Negative Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Neoplasm Metastasis; Melanoma |
Details
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