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Your Position: Home > TME Relevant Pathway > Plectin > PLN-H5249

Human Plectin / PLTN Protein, His Tag

  • Synonym
    Plectin,PLTN,PCN,HD1,Hemidesmosomal protein 1,PLEC1
  • Source
    Human Plectin, His Tag (PLN-H5249) is expressed from human 293 cells (HEK293). It contains AA Ala 4377 - Ala 4684 (Accession # Q15149-1).
    Predicted N-terminus: His
  • Molecular Characterization
    Online(Ala 4377 - Ala 4684) Q15149-1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 34.5 kDa. The protein migrates as 43-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human Plectin, His Tag (Cat. No. PLN-H5249) SDS-PAGE gel

Human Plectin, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

  • Background
    Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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