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TGA-H5141-100ug
$360.00
TGA-H5141-1mg (500ug × 2)
$2,380.00
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  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
  • 分子别名(Synonym)

    Transforming growth factor-alpha

  • 表达区间及表达系统(Source)

    Human TGF-alpha Protein, His Tag, premium grade (TGA-H5141) is expressed from E. coli cells. It contains AA Val 40 - Ala 89 (Accession # P01135-1).

    Predicted N-terminus: His

    It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

    Request for sequence
  • 蛋白结构(Molecular Characterization)

    TGF-alpha Structure

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 7.4 kDa. The protein migrates as 11 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • 内毒素(Endotoxin)

    Less than 0.01 EU per μg by the LAL method / rFC method.

  • 无菌(Sterility)

    Negative

  • 支原体(Mycoplasma)

    Negative.

  • 纯度(Purity)

    >90% as determined by SDS-PAGE.

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

Background

TGF-alpha is a normal physiological ligand for the EGF receptor. TGF-α and the EGF receptor are expressed in many developing and adult tissues, where TGF-α has been implicated in cell migration, growth, and differentiation.