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Your Position: Home > Antibody > Spike NTD > SPD-S164

Anti-SARS-CoV-2 Spike NTD Antibody, Human IgG1 (MALS verified)

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  • Source
    Anti-SARS-CoV-2 Spike NTD Antibody, Human IgG1 is isolated from a Spike NTD infected Human and is recombinantly produced from human 293 cells (HEK293)
  • Isotype
    Human IgG1/kappa
  • Specificity
    This product is a specific antibody specifically reacts with Spike NTD.
  • Application
    ELISA
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. For long term storage, the product is stable for up to 3 years at -70°C from date of receipt;
    2. For short term storage, the product is stable for up to 12 months at 2-8°C from date of receipt.
SDS-PAGE
Spike NTD SDS-PAGE

Anti-SARS-CoV-2 Spike NTD Antibody, Human IgG1 on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Spike NTD MALS images

The purity of Anti-SARS-CoV-2 Spike NTD Antibody, Human IgG1 (Cat. No. SPD-S164) is more than 90% and the molecular weight of this protein is around 135-155kDa verified by SEC-MALS.

Bioactivity-Elisa
 Spike NTD ELISA

Immobilized SARS-CoV-2 S1 protein NTD (A262S), His Tag (MALS verified) (S1D-C52H5) at 2μg/mL (100μL/well) can bind Anti-SARS-CoV-2 Spike NTD Antibody, Human IgG1 (Cat. No. SPD-S164) with a linear range of 0.12-125ng/mL (QC tested).

  • Background
    S protein has two functional regions, S1 and S2. S1 is composed of four domains, including N-amino-terminal domain (NTD) and receptor-binding domain (RBD), and binds to host cell receptor ACE2. Compared with RBD antibody, the neutralization ability of NTD antibody is weak, most of which can recognize the three-dimensional conformation of viral protein. In the NTD region of mutant strains, there are a large number of amino acid deletion and insertion, as well as numerous point mutations, most of which can escape the recognition and neutralization of NTD antibody.
  • Clinical and Translational Updates

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ETD of in-stock products: 2 business days

Price(USD) : $350.00

Price(USD) : $2800.00

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