Recombinant Monoclonal Anti-CD138 Antibody, Mouse (5G4)

描述/背景（Background）

CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes. CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury. It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells. Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics. Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.

种属（Host Species）

Mouse

克隆号（Clone）

5G4

适用方法（Application）

IHC

效价（Property）

1：500

状态（State）

Liquid

阳性对照（Positive Control）

Human Tonsil Tissues

克隆类型（Clonality）

Monoclonal

分子别名（Synonym）

SDC1, Syndecan, SYND1, CD138

研究领域（Research Field）

Cancer Drug Targets

抗体来源（Source）

Mouse

同种型（Isotype）

IgG

储存（Storage）

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.