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Your Position: Home > Antibody > SN38 > SN8-PLM685

HRP conjugated Monoclonal Anti-SN38 Antibody, Mouse IgG1

Antibody Internalization Detection Reagent (IGG-PZF2001) monitors endocytosis in live cells 

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  • Specificity

    Specifically recognizes the target-SN38.

  • Source

    HRP conjugated Monoclonal Anti-SN38 Antibody, Mouse IgG1 is a Mouse monoclonal antibody recombinantly expressed from HEK293 cells.

  • Isotype

    Mouse IgG1 | Mouse kappa

  • Conjugate

    HRP-Conjugated

  • Reactivity

    Chemical

  • Immunogen

    SN38-OVA

  • Application
    ApplicationRecommended Usage
    ELISA2-125 ng/mL 
  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Bioactivity-ELISA
 SN38 ELISA

Immobilized ADC-SN38 at 1 μg/mL (100 μL/well) can bind HRP conjugated Monoclonal Anti-SN38 Antibody, Mouse IgG1 (Cat. No. SN8-PLM685) with a linear range of 2-31.25 ng/mL (QC tested).

  • Background
    The 7-ethyl-10-hydroxycamptothecin (SN-38) is a topoisomerase I inhibitor (chemotherapeutic agent) used in cancer therapy. In a comparative study of SN-38 with a potent chemotherapeutic prodrug, irinotecan (CPT-11), SN-38 was found to be 1000-fold more cytotoxic against colorectal cancer cells as compared to irinotecan.
  • Clinical and Translational Updates

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Price(USD) : $615.00

Price(USD) : $4100.00

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