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Matrix Metalloproteinases

Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that play a significant role in degrading various substrates within the cell and in the extracellular matrix. This includes substrates such as myelin and other extracellular matrix proteins, cytokines & other growth factors, and cell adhesion-associated molecules.
As such, MMPs are an integral part of enabling cell migration, playing a role in physiological processes including ECM metabolism, cell migration, tissue repair, tissue remodeling, and many others. Different MMPs are expressed in different tissue types, with aberrant expression closely associated with the onset of diseases, including inflammatory, cardiovascular, and cancer diseases.
We now offer a wide range of highly active MMP recombinant proteins, including MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9 and MMP-10, supporting pathological mechanism research and drug development studies.

Product Features and Applications

Product Features

High Purity (>90%)

QC -verified High Enzymatic Activity

QC-verified batch-to-batch consistency

QC-verified batch-to-batch consistency

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Research Applications

Immunization

Antibody Screening

Functional Studies

Drug Hit-Lead Discovery

Enzyme Research

MMP Family Product List

Related Products

Assay Data

Purity Data

The purity of Human MMP-9, His Tag (Cat. No. MM9-H5229) is more than 90% and the molecular weight of this protein is around 50-70 kDa verified by SEC-MALS. The purity of the protein is greater than 95% verified by SDS-PAGE.

Enzyme Activity Data
Cat. No. Human MMP-9 Protein, His Tag (active enzyme) (MALS verified)
Substrate Mca-PLGL-Dpa-AR-NH2
Enzyme Activity
（pmol/min/μg） 		ACRO Product
（Cat. No.：MM9-H5229） 		Competitor R
>3,000(QC tested) >1,300
Cat. No. Human MMP-7 / PUMP1 Protein, His Tag (active enzyme)
Substrate Mca-PLGL-Dpa-AR-NH2
Enzyme Activity
（pmol/min/μg） 		ACRO Product
（Cat. No.：MM7-H5249） 		Competitor R
>600 (QC tested) >600
Cat. No. Human MMP-3 Protein, His Tag (active enzyme, MALS verified)
Substrate Mca-RPKPVE-Nval-WRK(Dnp)-NH2
Enzyme Activity
（pmol/min/μg） 		ACRO Product
（Cat. No.：MM3-H52H3） 		Competitor R
>422(QC tested) >150

Note: MMP series products need to be activated for use (Activation description: The proenzyme needs to be activated by APMA for an activated form)

  • Matrix Metalloproteinases
  • Product Features and Applications
  • MMP Family Product List
  • Related Products
  • Assay Data