CXCL9 Overview
Molecule Name
C-X-C motif chemokine 9
Synonyms
CMK, Humig, MIG, SCYB9, crg-10
Drug Development Progress
Drugs in Clinical Trials1
Approved Drugs0
Highest Development StagePhase 1 Clinical
Target Synonym
C-X-C motif chemokine 9，Gamma-interferon-induced monokine，Monokine induced by interferon-gamma (HuMIG; MIG)，Small-inducible cytokine B9，SCYB9，Crg-10，Humig，CMK，MIG，Monokine Induced By Gamma Interferon，Monokine Induced By Interferon-Gamma，Gamma-Interferon-Induced Monokine，Chemokine (C-X-C Motif) Ligand 9，Small-Inducible Cytokine B9，C-X-C Motif Chemokine 9，HuMIG
Background
CXCL9 is a small cytokine belonging to the CXC chemokine family that is also known as monokine induced by gamma interferon (MIG). CXCL9 is a chemokine that plays a role in immune responses, it can induce chemotaxis, promote differentiation and proliferation of leukocytes, and cause tissue extravasation. CXCL9 regulates immune cell migration, differentiation and activation by binding to CXCR3 receptor, such as CTLs, NK cells, NKT cells and macrophages. CXCL9 also participates in Th1 polarization and IFN-γ response.
Product Inquiry
Clinical Drug Information
| English Name | Research Code | Highest Development Stage | Company | Indication | Clinical Trial |
|---|---|---|---|---|---|
| NG-641 | EnAd-FAP-BiTE; EnAd-FAP-Tac; NG-641; NG-aFAP | Phase 1 Clinical | Akamis Bio Ltd, University Of Oxford | Squamous Cell Carcinoma of Head and Neck; Neoplasms, Glandular and Epithelial; Neoplasm Metastasis | Details |