IL-1beta

IL-1 beta, a polypeptide immune mediator, is a potent proinflammatory cytokine that initiates and amplifies a wide variety of effects associated with innate immunity and host responses to microbial invasion and tissue injury. There are two types of IL-1 beta receptors, IL-1RI and IL-1RII, with the former transducing signals in response to ligand binding and the latter acting as a “decoy” receptor, binding ligand without transducing a signal.