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Xanthine dehydrogenase

Xanthine dehydrogenase Overview

English NameXanthine dehydrogenaseApproved Drugs5
Drugs in Clinical Trials7Target SynonymXD，XDH，Xanthine Dehydrogenase，Xanthene Dehydrogenase，XAN1，XDHA，XOR，Xanthine oxidase，EC 1.7.2.2，EC:1.17.3.2，EC 1.17.1.4，EC:1.17.1.4，XO，Xanthine oxidoreductase，Xanthine dehydrogenase/oxidase
Highest Development StageApproved
English NameXanthine dehydrogenase
Target SynonymXD，XDH，Xanthine Dehydrogenase，Xanthene Dehydrogenase，XAN1，XDHA，XOR，Xanthine oxidase，EC 1.7.2.2，EC:1.17.3.2，EC 1.17.1.4，EC:1.17.1.4，XO，Xanthine oxidoreductase，Xanthine dehydrogenase/oxidase
Approved Drugs5
Drugs in Clinical Trials7
Highest Development StageApproved

Product Inquiry

Xanthine dehydrogenase Synonyms

XAN1, XO, XOR

Clinical Drug Information

English NameResearch CodeHighest Development StageCompanyIndicationClinical Trial
TigulixostatLC-350189; IBI-350; LR-19074Phase 3 ClinicalLg Chemical LtdHyperuricemia; Heart Diseases; Gout
Details
Oxipurinol （XORTX Therapeutics）XRx-008; XRx-101Phase 2 ClinicalXortx TherapeuticsPolycystic Kidney Diseases
Details
IBI-128IBI128; IBI-128Phase 2 ClinicalInnovent Biologics(Suzhou) Co LtdHyperuricemia; Metabolic Diseases; Arthritis, Gouty; Gout
Details
THDBH-151THDBH151; THDBH-151; [14C]THDBH151Phase 2 ClinicalDongbao Zixing (Hangzhou) Biological Medicine Co LtdGout
Details
Xrx-221Phase 1 ClinicalXortx TherapeuticsDiabetic Nephropathies
Details
HZN-457HZN-457Phase 1 ClinicalHorizon Therapeutics Ireland Dac
Details
HEC-93077HEC-93077; HEC93077Phase 1 ClinicalGuangdong Dongyangguang Pharmaceutical Co LtdHyperuricemia; Gout
Details

Marketed Drug Information

English NameResearch CodeHighest Development StageCompanyEarliest Brand NameEarliest Approval CountryEarliest IndicationEarliest Approval CompanyEarliest Approval DateIndicationClinical Trial
AllopurinolBW-56-158; ATH-008; NSC-1390ApprovedSebela Ireland LtdLopurin, Zyloric, Zyloprim, 路必利United StatesGout; HyperuricemiaCasper Pharma Llc1966-08-19Hand-Foot Syndrome; Hyperuricemia; Diabetes Mellitus, Type 2; Liver Cirrhosis; Angina Pectoris; Nephrolithiasis; Renal Insufficiency, Chronic; Inflammation; Gout
Details
FebuxostatTMX-67; TEI-6720; TMX-67XRApprovedTeijin Pharma风定宁, Uloric, 优立通, Adenuric, Febric, 瑞扬, Feburic, FebutazEUGoutMenarini International Operations Luxembourg Sa2008-04-21Hyperuricemia; Kidney Calculi; Pain; Renal Insufficiency; Angina Pectoris; Hypertension; Tumor Lysis Syndrome; Vascular Diseases; Cardiovascular Diseases; Colitis, Ulcerative; Gout; Kidney Failure, Chronic
Details
Allopurinol sodiumApprovedMylan NvAloprimUnited StatesHyperuricemia; GoutMylan Institutional Inc1996-05-17Hyperuricemia; Gout; Leishmaniasis
Details
Allopurinol/BenzbromaroneApprovedHyperuricemia
Details
TopiroxostatFYX-051; SK-0910ApprovedFuji Yakuhin Co LtdUriadec, TopiloricJapanHyperuricemia; GoutSanwa Kagaku Kenkyusho Co Ltd, Fuji Yakuhin Co Ltd2013-06-28Hyperuricemia; Diabetic Nephropathies; Gout
Details
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