Monoclonal Anti-Monkeypox-A30L Antibody, Human IgG1 (8A2) (MALS & SPR verified)

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A3L-M572-100ug
$415.00
A3L-M572-1mg (500ug × 2)
$2,735.00
A3L-M572
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  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
  • 抗体来源(Source)

    Monoclonal Anti-Monkeypox-A30L Antibody, Human IgG1 (8A2) is a chimeric monoclonal antibody recombinantly expressed from HEK293, which combines the variable region of a mouse monoclonal antibody with Human constant domain.

  • 克隆号(Clone)

    8A2

  • 亚型(Isotype)

    Human IgG1 | Human Kappa

  • 偶联(Conjugate)

    Unconjugated

  • 抗体类型(Antibody Type)

    Recombinant Monoclonal

  • 种属反应性(Reactivity)

    Virus

  • 免疫原(Immunogen)

    Recombinant Monkeypox virus (strain Zaire-96-I-16) A30L derived from human 293 cells.

  • 特异性(Specificity)

    This product is a specific antibody specifically reacts with A30L (MPXV).

  • 应用(Application)

    Application
    Recommended Usage
    ELISA
    0.5-125 ng/mL 
  • 纯度(Purity)

    90% as determined by SDS-PAGE.

    90% as determined by SEC-MALS.

  • 纯化(Purification)

    Protein A purified / Protein G purified

  • 制剂(Formulation)

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • 重构方法(Reconstitution)

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • 存储(Storage)

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • 质量管理控制体系(QMS)

    1. 质量管理体系(ISO, GMP)
    2. 质量优势
    3. 质控流程

Background

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa , multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. A30L is a Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).