APC-labeled Human CD47-coupled Magnetic Beads

Background

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

Application

This product is labeled by APC and coupled by CD47 protein in advance, no need to use fluorescent labeled secondary antibody, easy to flow cytometry.

Reconstitution

See Certificate of Analysis (CoA) for detailed instruction.

Storage

Store beads at 2° to 8°C and protected from direct light. Do not use after the expiration date shown on the label.

Formulation

Please contact us for detailed information.
Contact us for customized product form or formulation.

ACRO Quality Management System

1. QMS(ISO, GMP)
2. Quality Advantages
3. Quality Control Process