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BTK-H55H3-50ug
$310.00
BTK-H55H3-1mg
$2,680.00
BTK-H55H3
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  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
  • Synonyms

    AGMX1, ATK, BPK

  • Source

    Human BTK Protein, His Tag (BTK-H55H3) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Ser 659 (Accession # Q06187-1).

    Predicted N-terminus: Met 1

    Request for sequence
  • Molecular Characterization

    BTK Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 78.2 kDa. The protein migrates as 55 kDa,65 kDa and 85-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Background

The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]