Human Growth Hormone (GH) Protein, premium grade

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Cat. No. / Size
Price
Qty
GH1-H4118-20ug
$165.00
GH1-H4118-50ug
$290.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    Growth Hormone, GH, GH1, Somatotropin, GH-N

  • Source

    Human GH, premium grade (GH1-H4118) is expressed from E. coli cells. It contains AA Phe 27 - Phe 217 (Accession # P01241-1).

    Predicted N-terminus: Met

    It is produced under our rigorous quality control system that incorporates a comprehensive set of tests including sterility and endotoxin tests. Product performance is carefully validated and tested for compatibility for cell culture use or any other applications in the early preclinical stage. When ready to transition into later clinical phases, we also offer a custom GMP protein service that tailors to your needs. We will work with you to customize and develop a GMP-grade product in accordance with your requests that also meets the requirements for raw and ancillary materials use in cell manufacturing of cell-based therapies.

    Request for sequence
  • Molecular Characterization

    Growth Hormone Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries no "tag".

    The protein has a calculated MW of 22.3 kDa. The protein migrates as 21-22 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

  • Endotoxin

    Less than 0.1 EU per μg by the LAL method / rFC method.

  • Host Cell Protein

    <0.5 ng/µg of protein tested by ELISA.

  • Sterility

    Negative

  • Mycoplasma

    Negative

  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Supplied as 0.2 μm filtered solution in 20 mM Tris, 500 mM NaCl, 0.2 M Arginine, pH7.5 with glycerol as protectant.

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with dry ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -70°C for 24 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    Growth Hormone SDS-PAGE

    Human GH, premium grade on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • Bioactivity-ELISA

     Growth Hormone ELISA

    Immobilized Human GH, premium grade (Cat. No. GH1-H4118) at 2 μg/mL (100 μL/well) can bind Human GHR, His Tag (Cat. No. GHR-H5222) with a linear range of 0.1-2 ng/mL (QC tested).

    Protocol

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Background

Growth hormone (GH or GH-N) is also known as Somatotropin, Pituitary growth hormone. GH belongs to the somatotropin/prolactin family. Growth hormone (GH) may form monomer, dimer, trimer, tetramer and pentamer, by disulfide-linked or non-covalently associated, in homopolymeric and heteropolymeric combinations. GH can also form a complex either with GHBP or with the alpha2-macroglobulin complex. Growth hormone (GH) plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

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[Switzerland]: +41 800 040 012
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[North America]: 1 Innovation Way, Newark, DE 19711, USA
[Switzerland]: ACRObiosystems AG, c/o Zug Dammstrasse Centre AG, Dammstrasse 19, 6300 Zug Switzerland