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Integrin alpha 3 beta 1

Brief Information

Name:Integrin alpha 3/beta 1
Target Synonym:
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:0
Lastest Research Phase:Preclinical

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Cat. No. Species Product Description Structure Purity Feature
IT1-H52Wc Human Human Integrin alpha 3 beta 1 (ITGA3&ITGB1) Heterodimer Protein, His Tag&Tag Free
IT1-H52Wc-structure
IT1-H52Wc-sds

Synonym Name

Integrin alpha 3 beta 1,ITGA3&ITGB1

Background

Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.

Clinical and Translational Updates

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