Integrin alpha 3 beta 1

Integrin alpha 3 beta 1 is a crucial receptor involved in various biological processes, including cell adhesion, migration, and invasion. It is composed of an alpha subunit (ITGA3) and a beta subunit (ITGB1), which together form the integrin alpha 3 beta 1 complex. This complex plays a significant role in the formation of invadopodia, which are cell membrane protrusions that facilitate cell invasion. The integrin alpha 3 beta 1 complex interacts with various extracellular matrix proteins, such as fibronectin, laminin, and collagen, and is involved in processes like matrix degradation and cell invasion. It is also implicated in the maturation of integrin beta 1, which is essential for cell survival and growth.