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ROR1

ROR1 Product List

Cat. No. Species Product Description Structure Purity Feature
RO1-H5221 Human Human ROR1 (39-151, Ig-like domain) Protein
RO1-H5221-structure
RO1-H5221-sds
RO1-H821y Human Biotinylated Human ROR1 Protein, Avi Tag (Avitag™)
RO1-H821y-structure
RO1-H821y-sds
RO1-H5223 Human Human ROR1 (308-395, Kringle domain) Protein
RO1-H5223-structure
RO1-H5223-sds
RO1-H522y Human Human ROR1 Protein, His Tag
RO1-H522y-structure
RO1-H522y-sds
RO1-H5250 Human Human ROR1 Protein, Fc Tag
RO1-H5250-structure
RO1-H5250-sds
RO1-H5222 Human Human ROR1 (165-305, Frizzled domain) Protein
RO1-H5222-structure
RO1-H5222-sds
RO1-H82F4 Human Biotinylated Human ROR1 Protein, Fc Tag, Avi Tag (Avitag™)
RO1-H82F4-structure
RO1-H82F4-sds
RO1-M5221 Mouse Mouse ROR1 Protein
RO1-M5221-structure
RO1-M5221-sds
RO1-M5250 Mouse Mouse ROR1 Protein, Fc Tag
RO1-M5250-structure
RO1-M5250-sds
RO1-R5221 Rat Rat ROR1 Protein
RO1-R5221-structure
RO1-R5221-sds

ROR1 Molecule Synonym Name

ROR1,NTRKR1

ROR1 Molecule Background

Tyrosine-protein kinase transmembrane receptor ROR1 is also known as Neurotrophic tyrosine kinase, receptor-related 1 (NTRKR1), which belongs to the protein kinase superfamily or tyr protein kinase family or ROR subfamily. ROR1 contains 1 FZ (frizzled) domain, 1 Ig-like C2-type (immunoglobulin-like) domain, 1 kringle domain, 1 protein kinase domain. ROR1 is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. ROR1 could interact with casein kinase 1 epsilon (CK1¦Å) to activate phosphoinositide 3-kinase-mediated AKT phosphorylation and cAMP-response-element-binding protein (CREB), which was associated with enhanced tumor-cell growth.

ROR1 References

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