Login Register
icon_bulk_orderBulk order Acrobiosystems for English
0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > TNF-alpha

TNF-alpha

Brief Information

Name:Tumor necrosis factor α
Target Synonym:ICD1,Tumor necrosis factor,Tumor Necrosis Factor (TNF Superfamily, Member 2),Tumor Necrosis Factor Ligand 1F,Tumor Necrosis Factor-Alpha,TNF Superfamily, Member 2,TNF, Macrophage-Derived,TNF, Monocyte-Derived,APC1 Protein,TNLG1F,DIF,NTF,TNF-a,TNF-alpha,ICD2,N-terminal fragment,TNF,Tumor necrosis factor ligand superfamily member 2,Cachectin,TNFSF2,TNFA
Number of Launched Drugs:51
Number of Drugs in Clinical Trials:65
Lastest Research Phase:Approved

Product ListCompare or Buy

Part of Bioactivity data

TNA-H5228-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Human TNF-alpha, His Tag (active trimer) (MALS verified) (Cat. No. TNA-H5228) induces cytotoxicity effect on the WEH1-13VAR cells in the presence of the metabolic inhibitor actinomycin D. The EC50 for this effect is 0.013-0.074 ng/mL (Routinely tested).

TNA-H5228-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Neutralization assay shows that the cytotoxicity effect of Human TNF-alpha, His Tag (active trimer) (MALS verified) (Cat. No. TNA-H5228) was inhibited by increasing concentration of Adalimumab. The concentration of TNF-alpha used is 1 ng/mL. The IC50 is 26.8 ng/mL (Routinely tested).

TNA-Y59-SPR
Human_FcRn_Heterodimer_Protein_SPR

Monoclonal Anti-TNF-alpha antibody, Mouse IgG1 (16H5) (Cat. No. TNA-Y59) captured on CM5 chip via anti-mouse antibodies surface can bind Human TNF-alpha, His Tag (active trimer) (Cat. No. TNA-H5228) with an affinity constant of 0.274 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

TNA-Y58-SPR
Human_FcRn_Heterodimer_Protein_SPR

Monoclonal Anti-TNF-alpha antibody, Mouse IgG1 (13B8) (Cat. No. TNA-Y58) captured on CM5 chip via anti-mouse antibodies surface can bind Human TNF-alpha, His Tag (active trimer) (Cat. No. TNA-H5228) with an affinity constant of 0.323 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).

Synonym Name

DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα

Background

Tumor necrosis factor alpha (TNFα)  is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Etanercept biosimilar (Samsung Bioepis) SB-4 Approved Samsung Bioepis Eticovo, Benepali United States Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing; Arthritis, Psoriatic Samsung Bioepis Co Ltd 2016-01-13 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Infliximab biosimilar (Hisun Pharma) HS-626 Approved Zhejiang Hisun Pharmaceutical Co Ltd Mainland China Psoriasis Hisun Biopharmaceutical Co Ltd 2021-09-24 Psoriasis Details
Adalimumab biosimilar (Shanghai Henlius Biotech) HLX-03 Approved Shanghai Henlius Biotech Co Ltd 汉达远 Mainland China Uveitis, Intermediate; Uveitis, Posterior; Panuveitis Shanghai Henlius Biotech Co Ltd 2020-12-02 Uveitis, Intermediate; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Uveitis, Posterior; Plaque psoriasis; Panuveitis Details
Infliximab biosimilar (Celltrion) CT-P13 Approved Celltrion Remsima, Inflectra, Inflectra/Remsima, Flammegis Japan Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative; Crohn Disease Celltrion 2013-09-09 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Urologic Neoplasms; Crohn Disease Details
Adalimumab biosimilar (Hisun Pharma) HS-016 Approved Zhejiang Hisun Pharmaceutical Co Ltd 安健宁 Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing Hisun Biopharmaceutical Co Ltd 2019-12-06 Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
Opinercept E-11; ENIA-11 Approved Tsh Biopharm, Mycenax Biotech Inc TuNEX Taiwan Arthritis, Rheumatoid null 2017-01-01 Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Etanercept biosimilar (Hisun-Pfizer Pharmaceuticals) Approved Hisun-Pfizer AnBaiNuo Mainland China Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Wyeth Europa Ltd 2010-02-26 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Details
Infliximab biosimilar (Bionovis/The Instituto Vital Brazil) Approved Bionovis, The Instituto Vital Brazil Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Infliximab biosimilar (Shanghai Biomabs) CMAB-008; STI-002 Approved Shanghai Biomabs Pharmaceuticals Co Ltd 百类停, 类停 Mainland China Pediatric Crohn's disease; Crohn Disease; Spondylitis, Ankylosing; Colitis, Ulcerative; Arthritis, Rheumatoid; Psoriasis Taizhou Mabtech Pharmaceutical Co Ltd 2021-07-12 Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative; Crohn Disease Details
Infliximab biosimilar (Nichiiko Pharmaceutical/Aprogen) GS-071; NI-071 Approved Nichi-Iko Pharmaceutical Japan Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis null 2017-09-27 Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Etanercept biosimilar (Intas Biopharmaceuticals) Approved Intas Biopharmaceuticals Intacept India Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis Intas Biopharmaceuticals 2015-03-01 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Anti-tumour necrosis factor-alpha antibody Approved Materia Medica Holding Research And Production Company Artrofoon, Arthrofoon Arthritis, Rheumatoid; Osteoarthritis Details
Etanercept biosimilar (AryoGen Biopharma) Approved Aryogen Biopharma Altebrel Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Adalimumab biosimilar (Biocad) BCD-057 Approved Biocad Russian Federation Psoriasis Biocad 2019-03-01 Psoriasis Details
Etanercept biosimilar (Nanogen Biopharmaceutical) Approved Nanogen Biopharmaceutical Co Nanercept Vietnam Psoriasis; Arthritis, Rheumatoid Nanogen Biopharmaceutical Co 2019-01-01 Arthritis, Rheumatoid; Psoriasis Details
Adalimumab biosimilar (Celltrion) CT-P17 Approved Celltrion Yuflyma EU Crohn Disease; Uveitis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Hidradenitis Suppurativa; Psoriasis; Spondylitis, Ankylosing Celltrion Healthcare Hungary Kft 2021-02-11 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Etanercept biosimilar (PROBIOMED) Approved Probiomed Infinitam Mexico Arthritis, Rheumatoid Probiomed 2014-01-01 Arthritis, Rheumatoid Details
Adalimumab biosimilar (Boehringer Ingelheim) BI-695501 Approved C.H. Boehringer Sohn Ag & Co. Kg Cyltezo United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis Boehringer Ingelheim Gmbh 2017-08-25 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Adalimumab biosimilar (Reliance Life Sciences) R-TPR-021 Approved Reliance Life Sciences Adfrar IB India Colitis, Ulcerative; Psoriasis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Psoriatic Reliance Life Sciences, Torrent Pharma 2016-01-12 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic Details
Adalimumab biosimilar (Innovent Biologics) IBI-303 Approved Innovent Biologics(Suzhou) Co Ltd 苏立信 Mainland China Uveitis; Plaque psoriasis Innovent Biologics(Suzhou) Co Ltd 2020-09-02 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Uveitis; Plaque psoriasis Details
Infliximab biosimilar (AXXO) Approved Axxo Russian Federation Crohn Disease; Autoimmune Diseases Axxo 2013-01-01 Autoimmune Diseases; Crohn Disease Details
Etanercept biosimial (Sandoz) GP-2015 Approved Clariant Produkte (Schweiz) Ag Erelzi EU Arthritis, Juvenile; Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis Sandoz Gmbh 2016-08-30 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Infliximab biosimilar (Pfizer) PF-6438179; GP-1111; PF-06438179 Approved Pfizer Inc Ixifi, Zessly Japan Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Rheumatoid; Arthritis, Psoriatic Pfizer Inc 2017-12-13 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Crohn Disease Details
Adalimumab biosimilar (Pfizer) PF-06410293 Approved Pfizer Pharmaceuticals Ltd (China) Amsparity, Abrilada EU Crohn Disease; Uveitis; Psoriasis; Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative Pfizer Europe Ma Eeig 2019-11-15 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Infliximab biosimilar (Reliance Life Sciences) BOW-015; R-TPR-015 Approved Epirus Biopharmaceuticals Infimab Arthritis, Rheumatoid Details
Adalimumab biosimilar (Mylan/Biocon) BMO-2; MYL-1401-A Approved Biocon United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Mylan Pharmaceuticals Inc 2020-07-06 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Details
Etanercept biosimilar (Hanwha Chemical) HD-203; MK-8953 Approved Hanwha Chemical Davictrel Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Details
Etanercept biosimilar (Mochida) LBEC-0101 Approved Mochida Pharmaceutical Co Ltd Japan Arthritis, Juvenile; Arthritis, Rheumatoid null 2018-01-19 Arthritis, Rheumatoid; Arthritis, Juvenile Details
Infliximab biosimilar (Amgen) ABP-710 Approved Amgen Inc Avsola United States Plaque psoriasis; Pediatric ulcerative colitis; Pediatric Crohn's disease; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease Amgen Inc 2019-12-06 Arthritis, Rheumatoid; Pediatric Crohn's disease; Spondylitis, Ankylosing; Pediatric ulcerative colitis; Arthritis, Psoriatic; Colitis, Ulcerative; Plaque psoriasis; Crohn Disease Details
Infliximab TA-650 Approved Janssen Global Services Llc 类克, Remicade Japan Mucocutaneous Lymph Node Syndrome Mitsubishi Tanabe Pharma, Janssen Global Services Llc 1998-08-24 Giant Cell Arteritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Pediatric Crohn's disease; Sarcoidosis; Mucocutaneous Lymph Node Syndrome; Psoriasis; Pediatric ulcerative colitis; Arthritis, Psoriatic; Colitis, Ulcerative; Parapsoriasis; Uveitis; Pulmonary Disease, Chronic Obstructive; Crohn Disease; Behcet Syndrome Details
Etanercept biosimilar (Shanghai CP Guojian Pharmaceutical) 301S Approved Shanghai Cp Guojian Pharmaceutical Co Ltd, Cipla Gmbh Yisaipu, Etacept, 益赛普, Etanar Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Shanghai Cp Guojian Pharmaceutical Co Ltd 2005-06-20 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Details
Adalimumab biosimilar (Zydus Cadila) Approved Zydus Cadila Exemptia India Arthritis, Juvenile; Arthritis, Rheumatoid; Arthritis, Psoriatic; Spondylitis, Ankylosing Zydus Cadila 2014-12-09 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Psoriatic Details
Etanercept TNR-001 Approved Pfizer Pharmaceuticals Ltd (China), Amgen Inc 恩利, Enbrel, Lifmior Mainland China Psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid C.H. Boehringer Sohn Ag & Co. Kg 1998-11-02 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Pulmonary Fibrosis; Psoriasis; Arthritis, Psoriatic; Asthma; Inflammation; Arthritis; Plaque psoriasis Details
Adalimumab biosimilar (Samsung Bioepis) SB-5 Approved Samsung Bioepis Imraldi, Hadlima United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis Samsung Bioepis Co Ltd 2017-08-24 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Crohn Disease Details
Infliximab biosimilar (Merck & Co/Samsung Bioepis) SB-2 Approved Samsung Bioepis, Merck & Co Inc Renflexis, Flixabi United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Colitis, Ulcerative Samsung Bioepis Co Ltd 2016-05-26 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Etanercept biosimilar (Amega Biotech) Approved Amega Biotech Enerceptan Argentina Arthritis, Rheumatoid Amega Biotech 2012-01-01 Arthritis, Rheumatoid Details
Etanercept biosimilar (Mylan) YLB-113 Approved Rubin Ltd, Mylan Nv Nepexto EU Arthritis, Rheumatoid; Spondylarthropathies; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Plaque psoriasis Mylan Ire Healthcare Ltd 2020-05-20 Arthritis, Rheumatoid; Spondylarthropathies; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Psoriatic; Plaque psoriasis Details
Recombinant human type II tumor necrosis factor receptor-antibody fusion protein(Shanghai Cp Guojian) Approved Shanghai Cp Guojian Pharmaceutical Co Ltd 益赛普 Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Certolizumab pegol PHA-738144; CDP-870; CZP Approved Ucb Cimzia, Cimziat Mainland China Arthritis, Rheumatoid Ucb Pharma Sa 2008-04-22 Infertility, Male; Polyarticular Juvenile Idiopathic Arthritis; Arthritis, Rheumatoid; Spondylarthropathies; Spondylitis, Ankylosing; Spondylarthritis; Multiple Sclerosis; Psoriasis; Arthritis, Psoriatic; Osteoarthritis, Spine; Crohn Disease; Plaque psoriasis Details
Adalimumab biosimilar (Bio-Thera Solutions) BAT-1406 Approved Bio-Thera Solutions Ltd 格乐立 Mainland China Psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Uveitis Bio-Thera Solutions Ltd 2019-11-04 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Uveitis; Crohn Disease Details
Adalimumab biosimilar (Coherus BioSciences) CHS-1420 Approved Coherus Biosciences Yusimry United States Plaque psoriasis; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease Coherus Biosciences Inc 2021-12-17 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Plaque psoriasis; Crohn Disease Details
Adalimumab biosimilar (Fujifilm Kyowa Kirin Biologics/Mylan) FKB-327 Approved Fujifilm Kyowa Kirin Biologics Co Ltd Hulio EU Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Uveitis Viatris Ltd 2018-09-16 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Crohn Disease Details
PG-201 PG-201 Approved Viromed Layla South Korea Osteoarthritis Pmg Pharm Co Ltd 2012-01-01 Osteoarthritis, Knee; Osteoarthritis Details
Adalimumab biosimilar (CTTQ Pharma) Approved Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 2022-01-18 Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
Thalidomide NSC-66847; NSC-527179; K-17; VP-02 Approved Celgene Corp Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled Japan Leprosy, Lepromatous Fujimoto Pharmaceutical 1982-01-01 HIV Infections; Spondylitis, Ankylosing; Myelodysplastic Syndromes; Idiopathic Pulmonary Fibrosis; Multiple Myeloma; HIV Wasting Syndrome; Erythema Nodosum; Leprosy, Lepromatous; Carcinoma, Hepatocellular Details
Adalimumab biosimilar (Amgen) ABP-501 Approved Amgen Inc Amgevita, Amjevita, Solymbic EU Amgen Europe Bv 2016-09-23 Non-radiographic axial spondyloarthritis; Polyarticular Juvenile Idiopathic Arthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Crohn Disease; Plaque psoriasis Details
Pomalidomide IMID-4047; CDC-394; CC-4047; IMiD-1 Approved Celgene Corp Pomalyst, Imnovid, Actimid, Pomalyst/Imnovid, 安跃 Mainland China Multiple Myeloma Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 2013-02-08 Sarcoma; Anemia, Sickle Cell; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Metastasis; Sarcoma, Kaposi; Lymphoma, Non-Hodgkin; Amyloidosis; Primary Myelofibrosis; Lymphoma, Follicular; Prostatic Neoplasms; Medulloblastoma; Central Nervous System Neoplasms; Lung Diseases, Interstitial; Multiple Myeloma; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Scleroderma, Systemic; Solid tumours; Lymphoma, B-Cell; Bone Marrow Neoplasms Details
Golimumab rTNV148B; CNTO-148 Approved Janssen Global Services Llc Simponi aria, Simponi/Simponi aria, Simponi Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid Janssen Biologics Bv 2009-04-24 Diabetes Mellitus, Type 1; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Asthma; Colitis, Ulcerative; Arthritis, Psoriatic Details
Luminol sodium MP-1032 Approved Selvim, Metrio Psoriasis; Immune System Diseases null 1997-01-01 Coronavirus Disease 2019 (COVID-19); Immune System Diseases; Psoriasis Details
Adalimumab D2E7; ABT-D2E7; LU-200134 Approved Abbvie Inc 修美乐, Humira, Trudexa EU Uveitis; Psoriasis; Hidradenitis Suppurativa; Colitis, Ulcerative Stada Arzneimittel Ag 2002-12-31 Colitis, Ulcerative; Plaque psoriasis; Crohn Disease; Arthritis; Hidradenitis Suppurativa; Uveitis; Asthma; Arthritis, Psoriatic; Osteoarthritis, Knee; Pyoderma Gangrenosum; Psoriasis; Arthritis, Juvenile; Spondylarthritis; Pediatric Crohn's disease; Coronavirus Disease 2019 (COVID-19); Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Adalimumab biosimilar (Sandoz) GP-2017 Approved Sandoz Hefiya, Hyrimoz, Halimatoz United States Plaque psoriasis; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile Sandoz Inc 2018-07-26 Non-radiographic axial spondyloarthritis; Polyarticular Juvenile Idiopathic Arthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Plaque psoriasis; Crohn Disease Details
Adalimumab biosimilar (Fresenius Kabi) MSB-11022 Approved Merck Serono, Fresenius Kabi Ag Idacio, Kromeya EU Arthritis, Psoriatic; Colitis, Ulcerative; Arthritis, Rheumatoid; Uveitis; Psoriasis; Hidradenitis Suppurativa Fresenius Kabi Deutschland Gmbh 2019-04-02 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Lenalidomide IMID-5013; CDC-5013; CDC-501; CC-5013; IMiD-3; ENMD-0997 Approved Celgene Corp Revimid (former Brand Name), 瑞复美, Revlimid, Leavdo EU Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular Celgene Europe Bv 2005-12-27 Lymphoma, Follicular; Complex Regional Pain Syndromes; Crohn Disease; Carcinoma, Non-Small-Cell Lung; Melanoma; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Metastasis; Waldenstrom Macroglobulinemia; Thrombocytopenia; Lymphoma, Non-Hodgkin; Lymphoma; Lymphoma, T-Cell; Radiculopathy; Reflex Sympathetic Dystrophy; Prostatic Neoplasms; Lymphoma, Mantle-Cell; Lymphoma, B-Cell, Marginal Zone; Multiple Myeloma; Smoldering Multiple Myeloma; Lymphoma, Large B-Cell, Diffuse; Blood Protein Disorders; Leukemia-Lymphoma, Adult T-Cell; Myelodysplastic Syndromes; Paraproteinemias; Anemia; HIV Infections; Lymphoma, B-Cell; Solid tumours; Lymphoma, T-Cell, Peripheral; Hematologic Diseases; Leukemia, Myeloid Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
Adalimumab biosimilar (CinnaGen) Phase 3 Clinical Cinnagen Arthritis, Rheumatoid Details
ME-3183 ME-3183 Phase 1 Clinical Meiji Seika Pharma Co Ltd Psoriasis Details
Monoclonal Antibody (Mab) sB24M Phase 1 Clinical Pyoderma Gangrenosum Details
Recombinant human anti-TNFα monoclonal antibody (Huaota Biopharma) Phase 3 Clinical Shanghai Huaota Biopharmaceutical Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis; Plaque psoriasis Details
Certolizumab (Intrexon) AG-014 Phase 1 Clinical Intrexon Co Inflammatory Bowel Diseases Details
XTMAB-16 XTMAB-16 Phase 1 Clinical Xentria Inc Sarcoidosis Details
Thykamine PUR-0110; PCT-233 Phase 3 Clinical Purgenesis Technologies Dermatitis; Colitis, Ulcerative; Proctocolitis Details
Adalimumab biosimilar (AXXO) Clinical Axxo Arthritis, Rheumatoid; Arthritis, Psoriatic Details
Recombinant human anti-TNFα monoclonal antibody (Weimingdamu Biotech) Phase 1 Clinical Anhui Weiming Damu Biomedicine Co Ltd Arthritis, Rheumatoid Details
EYS-606 EYS-606 Phase 2 Clinical Eyevensys Uveitis Details
Etanercept biosimilar (Clover Biopharmaceuticals) SCB-808 Phase 3 Clinical Sichuan Sanyecao Bio-Pharmaceutical Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
AVX-470 AVX-470; AVX-1350; AVX-470h Phase 1 Clinical Avaxia Biologics Colitis, Ulcerative Details
IBPM005IX (Inbiopro Solutions) Clinical Inbiopro Solutions Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Arthritis, Psoriatic; Crohn Disease Details
Recombinant human anti-TNFα monoclonal antibody (Qilu Pharmaceutical) Phase 1 Clinical Qilu Pharmaceutical Co Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
Etanercept biosimilar (Suzhou Genemen Biotech) BF-02; GM-02 Phase 2 Clinical Suzhou Genemen Biotech Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Details
Etanercept biosimilar (Coherus Biosciences) CHS-0214; BAX-2200 Phase 3 Clinical Coherus Biosciences Arthritis, Rheumatoid; Psoriasis Details
CC-10015 CC-10015 Phase 2 Clinical Celgene Corp Sarcoidosis; Multiple Myeloma; Lupus Erythematosus, Systemic Details
Etanercept (Neurokine Pharmaceuticals) NP-1; NK-001 Clinical Pivot Pharmaceuticals Cognition Disorders Details
Adalimumab biosimilar (Eastern Biotech) JY-026 Phase 1 Clinical Beijing Eastern Biotech Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Crohn Disease Details
Infliximab biosimilar (Biocad) BCD-055 Phase 3 Clinical Biocad Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Ozoralizumab TS-152; ATN-103; PF-5230896; PF-05230896 Phase 3 Clinical Ablynx Arthritis, Rheumatoid Details
Anti-tumour necrosis factor alpha (Livzon) Phase 1 Clinical Livzon Pharmaceutical Group Inc Autoimmune Diseases Details
Adalimumab biosimilar (Alvotech) AVT-02 (Alvotech) Phase 3 Clinical Alvotech Autoimmune Diseases; Psoriasis Details
LY-3114062 LY3114062; LY-3114062 Phase 1 Clinical Eli Lilly And Company Arthritis Details
Adalimumab biosimilar (Alphamab) KN-002 Phase 1 Clinical Suzhou Alphamab Co Ltd Arthritis, Rheumatoid; Asthma Details
Adalimumab biosimilar (Hetero Drugs) Phase 3 Clinical Hetero Drugs Arthritis, Rheumatoid Details
Infliximab biosimilar (Genor Biopharma) GB-242 Phase 3 Clinical Genor Biopharma Co Ltd Arthritis, Rheumatoid Details
Adalimumab biosimilar (LG Life Sciences) LBAL Phase 3 Clinical Mochida Pharmaceutical Co Ltd, Lg Chemical Ltd Arthritis, Rheumatoid Details
Adalimumab biosimilar (Genor Biopharma) GB-232; BCD-100 Phase 2 Clinical Genor Biopharma Co Ltd Carcinoma, Renal Cell; Arthritis, Rheumatoid; Lung Neoplasms; Melanoma Details
Human anti-TNFα monoclonal antibody (DZM Biotech) Phase 1 Clinical Dzm Biotech Ltd Arthritis, Rheumatoid Details
Recombinant anti-TNFα antibody (Shanghai Xiesheng Medicine) Phase 1 Clinical Shanghai Harmony Pharmaceutical Technology Co Ltd Details
Adalimumab biosimilar (Oncobiologics) ONS-3010 Phase 3 Clinical Outlook Therapeutics Psoriasis Details
Wogonin Phase 1 Clinical Shandong Buchang Pharmaceuticals Co Ltd, Hefei Cosource Medicine Technology, Daewoong Pharmaceutical Co Ltd, China Pharmaceutical University Respiratory Tract Infections; Neoplasms Details
Recombinant human monoclonal antibody specific for human tumor necrosis factor (North China Pharmaceutical) Phase 1 Clinical North China Pharmaceutical Company Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing; Autoimmune Diseases; Psoriasis Details
Infliximab biosimilar (Ospedale San Raffaele) Phase 1 Clinical Ospedale San Raffaele Takayasu Arteritis Details
Remtolumab ABT-122; D2E7-GS10-B6-17 Phase 2 Clinical Abbvie Inc Arthritis, Rheumatoid; Arthritis, Psoriatic; Rheumatic Diseases Details
Adalimumab biosimilar (Danhong Pharma) BC-002 Phase 3 Clinical Shandong Danhong Pharmaceutical Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Adalimumab biosimilar (Prestige BioPharma) PBP-1502 Phase 1 Clinical Prestige Biopharma Arthritis Details
Licaminlimab OCS-02; ESBA-1622; LME-636 Phase 2 Clinical Oculis Pharma Dry Eye Syndromes; Uveitis, Anterior; Xerophthalmia Details
Adalimumab biosimilar (Hualan Biological Engineering) Phase 3 Clinical Hualan Genetic Engineering Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis Details
Adalimumab biosimilar (Tonghua Dongbao Pharmaceutical) Phase 3 Clinical Tonghua Dongbao Pharmaceutical Co Ltd Arthritis, Rheumatoid; Plaque psoriasis Details
Recombinant anti-TNFα monoclonal antibody (Wuhan Institute of Biological Products) Phase 3 Clinical Wuhan Institute Of Biological Products Co Ltd Plaque psoriasis Details
Adalimumab biosimillar(Huabo) Onco-3010; HOT-3010 Clinical Huabo Biopharm Co Ltd Arthritis, Rheumatoid Details
Tanfanercept HBM-9036; HL-036 Phase 3 Clinical Hanall Dry Eye Syndromes; Xerophthalmia Details
Recombinant anti-TNFα monoclonal antibody (Livzon Group) AT-132; LZM-001 Phase 2 Clinical Livzon Pharmaceutical Group Inc Arthritis, Rheumatoid Details
JNJ-61178104 JNJ-61178104 Phase 1 Clinical Janssen Global Services Llc Autoimmune Diseases Details
JNJ-63823539 JNJ-63823539 Phase 1 Clinical Janssen Global Services Llc Arthritis, Rheumatoid Details
COVA-322 COVA-322 Phase 2 Clinical Covagen Psoriasis Details
Adalimumab biosimilar(Incepta) Phase 3 Clinical Incepta Pharmaceuticals Ltd Arthritis, Rheumatoid Details
Hemay007 Hemay-007 Phase 2 Clinical Tianjin Hemay Bio-Tech Co Ltd Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Colitis, Ulcerative Details
SCB-219 SCB-219 Phase 1 Clinical Sichuan Sanyecao Bio-Pharmaceutical Co Ltd Purpura, Thrombocytopenic, Idiopathic; Thrombocytopenia Details
ND-009 ND-009 Phase 1 Clinical Numab Therapeutics Ag, Tillotts Pharma Ag Inflammation Details
Isomyosamine MYMD-1 Phase 2 Clinical Mymd Pharmaceuticals Inc Hashimoto Disease; Healthy Aging Details
Efprezimod alfa CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 Phase 3 Clinical Oncoimmune Leukemia; Hematopoietic stem cell transplantation (HSCT); HIV Infections; Graft vs Host Disease; Coronavirus Disease 2019 (COVID-19); Myelodysplastic Syndromes; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Dyslipidemias; Leukemia, Myeloid, Acute; Melanoma Details
Hemay-005 Hemay-005 Phase 3 Clinical Hainan Hailing Chemipharma Corporation Ltd, Tianjin Hemay Pharmaceutical Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Behcet Syndrome; Plaque psoriasis; Dermatitis, Atopic Details
PM-1016 PM1016; TILT-123 Phase 2 Clinical Tilt Biotherapeutics Ltd Solid tumours; Squamous Cell Carcinoma of Head and Neck; Melanoma Details
Golimumab biosimilar (Bio-thera) BAT-2506 Phase 3 Clinical Bio-Thera Solutions Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Arthritis Details

This web search service is supported by Google Inc.

totop
Call us
Call us
North America: +1 800-810-0816 (Toll Free)
Asia & Pacific: +86 400-682-2521
Fax
Fax
+1 888-377-6111
Address
Address
1 Innovation Way, Newark, DE 19711, USA

Leave a message