0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > TNF-alpha

TNF-alpha

Brief Information

Name:Tumor necrosis factor α
Target Synonym:Tumor Necrosis Factor (TNF Superfamily, Member 2),Tumor Necrosis Factor Ligand 1F,Tumor Necrosis Factor-Alpha,TNF Superfamily, Member 2,TNF, Macrophage-Derived,TNF, Monocyte-Derived,APC1 Protein,TNLG1F,DIF,ICD1,Tumor necrosis factor,NTF,TNF-a,TNF-alpha,IC
Number of Launched Drugs:46
Number of Drugs in Clinical Trials:63
Lastest Research Phase:Approved

Product ListCompare or Buy

Part of Bioactivity data

TNA-H5228-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Human TNF-alpha, His Tag (active trimer) (MALS verified) (Cat. No. TNA-H5228) induces cytotoxicity effect on the WEH1-13VAR cells in the presence of the metabolic inhibitor actinomycin D. The EC50 for this effect is 0.013-0.074 ng/mL (Routinely tested).

TNA-H5228-Cell-based assay
Human FcRn Heterodimer Protein Cell_Base

Neutralization assay shows that the cytotoxicity effect of Human TNF-alpha, His Tag (active trimer) (MALS verified) (Cat. No. TNA-H5228) was inhibited by increasing concentration of Adalimumab. The concentration of TNF-alpha used is 1 ng/mL. The IC50 is 26.8 ng/mL (Routinely tested).

TNA-H5228-SPR
Human_FcRn_Heterodimer_Protein_SPR

Humira (Adalimumab) captured on CM5 chip via anti-human IgG Fc antibodies surface, can bind Human TNF-alpha, His Tag (active trimer) (MALS verified) (Cat. No. TNA-H5228) with an affinity constant of 0.244 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

TNA-H4211-SPR
Human_FcRn_Heterodimer_Protein_SPR

Humira (Adalimumab) captured on CM5 chip via anti-human IgG Fc antibodies surface, can bind ActiveMax® Human TNF-alpha, Tag Free, low endotoxin (active trimer) (MALS verified) (Cat. No. TNA-H4211) with an affinity constant of 0.255 nM as determined in a SPR assay (Biacore T200) (Routinely tested).

Synonym Name

DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα

Background

Tumor necrosis factor alpha (TNFα)  is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

Clinical and Translational Updates

Public Drug Information

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Etanercept biosimilar (Samsung Bioepis) SB-4 Approved Samsung Bioepis Eticovo, Benepali United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis Samsung Bioepis Co Ltd 2016-01-13 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Anti-tumour necrosis factor-alpha antibody Approved Materia Medica Holding Research And Production Company Artrofoon, Arthrofoon Arthritis, Rheumatoid; Osteoarthritis Details
Etanercept biosimilar (Mycenax Biotech/TSH Biopharm) ENIA-11; E-11 Approved Mycenax Biotech Inc, Tsh Biopharm TuNEX Taiwan Arthritis, Rheumatoid null 2017-01-01 Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Etanercept biosimilar (Nanogen Biopharmaceutical) Approved Nanogen Biopharmaceutical Co Nanercept Vietnam Psoriasis; Arthritis, Rheumatoid Nanogen Biopharmaceutical Co 2019-01-01 Arthritis, Rheumatoid; Psoriasis Details
Infliximab biosimilar (Reliance Life Sciences) BOW-015; R-TPR-015 Approved Epirus Biopharmaceuticals Infimab Arthritis, Rheumatoid Details
Adalimumab biosimilar (Mylan/Biocon) BMO-2; MYL-1401-A Approved Biocon United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Mylan Pharmaceuticals Inc 2020-07-06 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Details
Etanercept biosimilar (Hisun-Pfizer Pharmaceuticals) Approved Hisun-Pfizer AnBaiNuo Mainland China Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Wyeth Europa Ltd 2010-02-26 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Details
Etanercept biosimilar (PROBIOMED) Approved Probiomed Infinitam Mexico Arthritis, Rheumatoid Probiomed 2014-01-01 Arthritis, Rheumatoid Details
Etanercept biosimilar (AryoGen Biopharma) Approved Aryogen Biopharma Altebrel Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Etanercept biosimilar (Hanwha Chemical) HD-203; MK-8953 Approved Hanwha Chemical Davictrel Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Details
Infliximab biosimilar (Bionovis/The Instituto Vital Brazil) Approved Bionovis, The Instituto Vital Brazil Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Etanercept biosimilar (Shanghai Celgen) Approved Shanghai Celgen Bio-Pharmaceutical Co Ltd Psoriasis Details
Etanercept biosimilar (Intas Biopharmaceuticals) Approved Intas Biopharmaceuticals Intacept India Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis Intas Biopharmaceuticals 2015-03-01 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Adalimumab biosimilar (Amgen) ABP-501 Approved Amgen Inc Amgevita, Amjevita, Solymbic EU Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease Amgen Europe Bv 2016-09-23 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Crohn Disease Details
Etanercept biosimilar (Amega Biotech) Approved Amega Biotech Enerceptan Argentina Arthritis, Rheumatoid Amega Biotech 2012-01-01 Arthritis, Rheumatoid Details
Etanercept biosimilar (Mylan) YLB-113 Approved Mylan Nv, Rubin Ltd Nepexto EU Arthritis, Rheumatoid; Psoriasis; Spondylarthropathies; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile Mylan Ire Healthcare Ltd 2020-05-20 Arthritis, Rheumatoid; Spondylarthropathies; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Adalimumab biosimilar (Fujifilm Kyowa Kirin Biologics/Mylan) FKB-327 Approved Fujifilm Kyowa Kirin Biologics Co Ltd Hulio EU Crohn Disease; Uveitis; Hidradenitis Suppurativa; Colitis, Ulcerative; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid Mylan Sas 2018-09-16 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Adalimumab biosimilar (Reliance Life Sciences) R-TPR-021 Approved Reliance Life Sciences Adfrar IB India Colitis, Ulcerative; Psoriasis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Psoriatic Reliance Life Sciences, Torrent Pharma 2016-01-12 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic Details
Adalimumab biosimilar (Biocad) BCD-057 Approved Biocad Russian Federation Psoriasis Biocad 2019-03-01 Psoriasis Details
Adalimumab biosimilar (Zydus Cadila) Approved Zydus Cadila Exemptia India Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Arthritis, Psoriatic Zydus Cadila 2014-12-09 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Arthritis, Psoriatic Details
Etanercept biosimilar (Mochida) LBEC-0101 Approved Mochida Pharmaceutical Co Ltd Japan Arthritis, Juvenile; Arthritis, Rheumatoid null 2018-01-19 Arthritis, Rheumatoid; Arthritis, Juvenile Details
PG-201 PG-201 Approved Viromed Layla South Korea Osteoarthritis Pmg Pharm Co Ltd 2012-01-01 Osteoarthritis, Knee; Osteoarthritis Details
Adalimumab biosimilar (Innovent Biologics) IBI-303 Approved Innovent Biologics(Suzhou) Co Ltd 苏立信 Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Innovent Biologics(Suzhou) Co Ltd 2020-09-02 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Details
Adalimumab biosimilar (Bio-Thera Solutions) BAT-1406 Approved Bio-Thera Solutions Ltd 格乐立 Mainland China Uveitis; Psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease Bio-Thera Solutions Ltd 2019-11-04 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Uveitis; Crohn Disease Details
Etanercept biosimilar (Shanghai CP Guojian Pharmaceutical) 301S Approved Shanghai Cp Guojian Pharmaceutical Co Ltd, Cipla Gmbh Yisaipu, Etacept, 益赛普, Etanar Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Shanghai Cp Guojian Pharmaceutical Co Ltd 2005-06-20 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Details
Infliximab biosimilar (Nichiiko Pharmaceutical/Aprogen) GS-071; NI-071 Approved Nichi-Iko Pharmaceutical, Aprogen Japan Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis null 2017-09-27 Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Etanercept TNR-001 Approved Pfizer Pharmaceuticals Ltd (China), Amgen Inc 恩利, Enbrel, Lifmior Mainland China Psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid C.H. Boehringer Sohn Ag & Co. Kg 1998-11-02 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Pulmonary Fibrosis; Psoriasis; Arthritis, Psoriatic; Asthma; Inflammation; Arthritis; Plaque psoriasis Details
Infliximab TA-650 Approved Janssen Global Services Llc 类克, Remicade Japan Mucocutaneous Lymph Node Syndrome Mitsubishi Tanabe Pharma, Janssen Global Services Llc 1998-08-24 Giant Cell Arteritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Pediatric Crohn's disease; Sarcoidosis; Mucocutaneous Lymph Node Syndrome; Psoriasis; Pediatric ulcerative colitis; Colitis, Ulcerative; Arthritis, Psoriatic; Parapsoriasis; Uveitis; Pulmonary Disease, Chronic Obstructive; Crohn Disease; Behcet Syndrome Details
Adalimumab D2E7; ABT-D2E7; LU-200134 Approved Abbvie Inc 修美乐, Humira, Trudexa Mainland China Pediatric Crohn's disease Abbott Laboratories Ltd 2002-12-31 Pyoderma Gangrenosum; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Pediatric Crohn's disease; Coronavirus Disease 2019 (COVID-19); Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Osteoarthritis, Knee; Arthritis, Psoriatic; Asthma; Uveitis; Hidradenitis Suppurativa; Arthritis; Crohn Disease; Plaque psoriasis Details
Certolizumab pegol PHA-738144; CDP-870; CZP Approved Ucb Cimzia, Cimziat Mainland China Arthritis, Rheumatoid Ucb Pharma Sa 2008-04-22 Infertility, Male; Arthritis, Rheumatoid; Spondylarthropathies; Spondylitis, Ankylosing; Spondylarthritis; Multiple Sclerosis; Psoriasis; Arthritis, Psoriatic; Osteoarthritis, Spine; Crohn Disease; Plaque psoriasis Details
Golimumab rTNV148B; CNTO-148 Approved Janssen Global Services Llc Simponi aria, Simponi/Simponi aria, Simponi Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid Janssen Biologics Bv 2009-04-24 Diabetes Mellitus, Type 1; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Asthma; Colitis, Ulcerative; Arthritis, Psoriatic Details
Infliximab biosimilar (Amgen) ABP-710 Approved Amgen Inc Avsola United States Pediatric Crohn's disease; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Pediatric ulcerative colitis Amgen Inc 2019-12-06 Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Pediatric ulcerative colitis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Adalimumab biosimilar (Celltrion) CT-P17 Approved Celltrion Yuflyma EU Crohn Disease; Uveitis; Arthritis, Rheumatoid; Colitis, Ulcerative; Hidradenitis Suppurativa; Psoriasis; Spondylitis, Ankylosing; Arthritis, Psoriatic Celltrion Healthcare Hungary Kft 2021-02-11 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Infliximab biosimilar (AXXO) Approved Axxo Russian Federation Crohn Disease; Autoimmune Diseases Axxo 2013-01-01 Autoimmune Diseases; Crohn Disease Details
Adalimumab biosimilar (Samsung Bioepis) SB-5 Approved Samsung Bioepis Imraldi, Hadlima United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis Samsung Bioepis Co Ltd 2017-08-24 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Crohn Disease Details
Pomalidomide CDC-394; CC-4047; IMiD-1; IMID-4047 Approved Celgene Corp Pomalyst, Imnovid, Actimid, Pomalyst/Imnovid, 安跃 Mainland China Multiple Myeloma Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 2013-02-08 Central Nervous System Neoplasms; Anemia, Sickle Cell; Sarcoma, Kaposi; Leukemia, Lymphocytic, Chronic, B-Cell; Neoplasm Metastasis; Lymphoma, Non-Hodgkin; Primary Myelofibrosis; Lymphoma, Follicular; Prostatic Neoplasms; Sarcoma; Medulloblastoma; Lung Diseases, Interstitial; Multiple Myeloma; Hodgkin Disease; Lymphoma, Large B-Cell, Diffuse; Scleroderma, Systemic; Lymphoma, B-Cell; Bone Marrow Neoplasms; Solid tumours Details
Adalimumab biosimilar (Pfizer) PF-06410293 Approved Pfizer Pharmaceuticals Ltd (China) Amsparity, Abrilada EU Crohn Disease; Uveitis; Psoriasis; Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative Pfizer Europe Ma Eeig 2019-11-15 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Infliximab biosimilar (Merck & Co/Samsung Bioepis) SB-2 Approved Samsung Bioepis, Merck & Co Inc Renflexis, Flixabi United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Colitis, Ulcerative Samsung Bioepis Co Ltd 2016-05-26 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Adalimumab biosimilar (Hisun Pharma) HS-016 Approved Zhejiang Hisun Pharmaceutical Co Ltd 安健宁 Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing Hisun Biopharmaceutical Co Ltd 2019-12-06 Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
Infliximab biosimilar (Shanghai Biomabs) CMAB-008; STI-002 Approved Shanghai Biomabs Pharmaceuticals Co Ltd 百类停, 类停 Mainland China Pediatric Crohn's disease; Crohn Disease; Spondylitis, Ankylosing; Colitis, Ulcerative; Arthritis, Rheumatoid; Psoriasis Taizhou Mabtech Pharmaceutical Co Ltd 2021-07-12 Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative; Crohn Disease Details
Adalimumab biosimilar (Shanghai Henlius Biotech) HLX-03 Approved Shanghai Henlius Biotech Co Ltd 汉达远 Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Shanghai Henlius Biotech Co Ltd 2020-12-02 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Plaque psoriasis Details
Adalimumab biosimilar (Boehringer Ingelheim) BI-695501 Approved C.H. Boehringer Sohn Ag & Co. Kg Cyltezo United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis Boehringer Ingelheim Gmbh 2017-08-25 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Luminol sodium MP-1032 Approved Selvim, Metrio Psoriasis; Immune System Diseases null 1997-01-01 Coronavirus Disease 2019 (COVID-19); Immune System Diseases; Psoriasis Details
Infliximab biosimilar (Celltrion) CT-P13 Approved Celltrion Remsima, Inflectra, Inflectra/Remsima, Flammegis Japan Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative; Crohn Disease Celltrion 2013-09-09 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Urologic Neoplasms; Crohn Disease Details
Infliximab biosimilar (Pfizer) PF-6438179; GP-1111; PF-06438179 Approved Pfizer Inc Ixifi, Zessly Japan Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Rheumatoid; Arthritis, Psoriatic Pfizer Inc 2017-12-13 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Crohn Disease Details
Etanercept biosimial (Sandoz) GP-2015 Approved Clariant Produkte (Schweiz) Ag Erelzi EU Arthritis, Juvenile; Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Rheumatoid; Psoriasis Sandoz Gmbh 2016-08-30 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Thalidomide NSC-66847; NSC-527179; K-17; VP-02 Approved Celgene Corp Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled Japan Leprosy, Lepromatous Fujimoto Pharmaceutical 1982-01-01 HIV Infections; Spondylitis, Ankylosing; Myelodysplastic Syndromes; Idiopathic Pulmonary Fibrosis; Multiple Myeloma; HIV Wasting Syndrome; Erythema Nodosum; Leprosy, Lepromatous; Carcinoma, Hepatocellular Details
Lenalidomide IMID-5013; CDC-5013; CDC-501; ENMD-0997; CC-5013; IMiD-3 Approved Celgene Corp 瑞复美, Revlimid, Revimid (former Brand Name) EU Lymphoma, B-Cell, Marginal Zone; Lymphoma, Follicular Celgene Europe Bv 2005-12-27 Radiculopathy; Carcinoma, Non-Small-Cell Lung; Crohn Disease; Neoplasm Metastasis; Melanoma; Complex Regional Pain Syndromes; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma; Waldenstrom Macroglobulinemia; Thrombocytopenia; Leukemia, Myeloid, Acute; Lymphoma, T-Cell; Lymphoma, Non-Hodgkin; Prostatic Neoplasms; Lymphoma, Follicular; Reflex Sympathetic Dystrophy; Leukemia, Myeloid; Lymphoma, Mantle-Cell; Multiple Myeloma; Smoldering Multiple Myeloma; Lymphoma, Large B-Cell, Diffuse; Myelodysplastic Syndromes; Blood Protein Disorders; Leukemia-Lymphoma, Adult T-Cell; Paraproteinemias; Anemia; Lymphoma, B-Cell; HIV Infections; Solid tumours; Hematologic Diseases; Lymphoma, B-Cell, Marginal Zone; Lymphoma, T-Cell, Peripheral Details
Adalimumab biosimilar (Sandoz) GP-2017 Approved Sandoz Hefiya, Hyrimoz, Halimatoz United States Plaque psoriasis; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile Sandoz Inc 2018-07-26 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Plaque psoriasis; Crohn Disease Details
Adalimumab biosimilar (Fresenius Kabi) MSB-11022 Approved Merck Serono, Fresenius Kabi Ag Idacio, Kromeya EU Psoriasis; Hidradenitis Suppurativa Fresenius Kabi Deutschland Gmbh 2019-04-02 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details

Clinical Drug Information

Name Research Code Research Phase Company Indications Clinical Trials
JNJ-63823539 JNJ-63823539 Phase 1 Clinical Janssen Global Services Llc Arthritis, Rheumatoid Details
Ozoralizumab TS-152; ATN-103; PF-5230896; PF-05230896 Phase 3 Clinical Ablynx Arthritis, Rheumatoid Details
Recombinant human anti-TNFα monoclonal antibody (Qilu Pharmaceutical) Phase 1 Clinical Qilu Pharmaceutical Co Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
AVX-470 AVX-470; AVX-1350; AVX-470h Phase 1 Clinical Avaxia Biologics Colitis, Ulcerative Details
IBPM005IX (Inbiopro Solutions) Clinical Inbiopro Solutions Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Arthritis, Psoriatic; Crohn Disease Details
Adalimumab biosimilar (Genor Biopharma) GB-232; BCD-100 Phase 2 Clinical Genor Biopharma Co Ltd Carcinoma, Renal Cell; Arthritis, Rheumatoid; Lung Neoplasms; Melanoma Details
Anti-tumour necrosis factor alpha (Livzon) Phase 1 Clinical Livzon Pharmaceutical Group Inc Autoimmune Diseases Details
Thykamine PUR-0110; PCT-233 Phase 3 Clinical Purgenesis Technologies Dermatitis; Colitis, Ulcerative; Proctocolitis Details
Etanercept (Neurokine Pharmaceuticals) NP-1; NK-001 Clinical Pivot Pharmaceuticals Cognition Disorders Details
COVA-322 COVA-322 Phase 2 Clinical Covagen Psoriasis Details
ABT-122 ABT-122; D2E7-GS10-B6-17 Phase 2 Clinical Abbvie Inc Arthritis, Rheumatoid; Rheumatic Diseases; Arthritis, Psoriatic Details
Human anti-TNFα monoclonal antibody (DZM Biotech) Phase 1 Clinical Daqing Dongzhuming Biotechnology Co Ltd Arthritis, Rheumatoid Details
Adalimumab biosimilar (Alvotech) AVT-02 (Alvotech) Phase 3 Clinical Alvotech Autoimmune Diseases; Psoriasis Details
Adalimumab biosimilar (Prestige BioPharma) PBP-1502 Phase 1 Clinical Prestige Biopharma Arthritis Details
V-565 V-565 Phase 2 Clinical Vhsquared Colitis, Ulcerative; Crohn Disease Details
Recombinant anti-TNFα antibody (Shanghai Xiesheng Medicine) Phase 1 Clinical Shanghai Harmony Pharmaceutical Technology Co Ltd Details
Infliximab biobetter (Mabtech/Sorrento) STI-002 Phase 3 Clinical Taizhou Maibo Taike Biotechnology Co Ltd, Sorrento Therapeutics Arthritis, Rheumatoid Details
Adalimumab biosimilar (Oncobiologics) ONS-3010 Phase 3 Clinical Outlook Therapeutics Psoriasis Details
Adalimumab biosimilar (Coherus BioSciences) CHS-1420 Phase 3 Clinical Coherus Biosciences Psoriasis Details
Adalimumab biosimilar (Hetero Drugs) Phase 3 Clinical Hetero Drugs Arthritis, Rheumatoid Details
Recombinant human anti-TNFα monoclonal antibody (Weimingdamu Biotech) Phase 1 Clinical Anhui Weiming Damu Biomedicine Co Ltd Arthritis, Rheumatoid Details
EYS-606 EYS-606 Phase 2 Clinical Eyevensys Uveitis Details
Adalimumab biosimilar (CinnaGen) Phase 3 Clinical Cinnagen Arthritis, Rheumatoid Details
Certolizumab (Intrexon) AG-014 Phase 1 Clinical Intrexon Co Inflammatory Bowel Diseases Details
Infliximab biosimilar (Biocad) BCD-055 Phase 3 Clinical Biocad Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Etanercept biosimilar (Clover Biopharmaceuticals) SCB-808 Phase 3 Clinical Sichuan Sanyecao Bio-Pharmaceutical Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
OCS-02 OCS-02; ESBA-1622; LME-636 Phase 2 Clinical Oculis Pharma Dry Eye Syndromes; Uveitis, Anterior; Xerophthalmia Details
Etanercept biosimilar (Coherus Biosciences) CHS-0214; BAX-2200 Phase 3 Clinical Coherus Biosciences Arthritis, Rheumatoid; Psoriasis Details
HMPL-004 (Hutchison Medipharma) HMPL-004 Phase 3 Clinical Hutchison Medipharma Ltd Lupus Erythematosus, Systemic; Colitis, Ulcerative; Crohn Disease Details
CC-10015 CC-10015 Phase 2 Clinical Celgene Corp Sarcoidosis; Multiple Myeloma; Lupus Erythematosus, Systemic Details
Adalimumab biosimilar (LG Life Sciences) LBAL Phase 3 Clinical Mochida Pharmaceutical Co Ltd, Lg Chemical Ltd Arthritis, Rheumatoid Details
Recombinant anti-TNFα monoclonal antibody (Wuhan Institute of Biological Products) Phase 3 Clinical Wuhan Institute Of Biological Products Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Plaque psoriasis Details
Adalimumab biosimilar (Hualan Biological Engineering) Phase 3 Clinical Hualan Genetic Engineering Co Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis Details
Recombinant anti-TNFα monoclonal antibody (Livzon Group) AT-132; LZM-001 Phase 2 Clinical Livzon Pharmaceutical Group Inc Arthritis, Rheumatoid Details
Adalimumab biosimilar (Beijing Luzhu Biotechnology) Phase 1 Clinical Beijing Lvzhu Biological Technology Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis Details
Infliximab biosimilar (Genor Biopharma) GB-242 Phase 3 Clinical Genor Biopharma Co Ltd Arthritis, Rheumatoid Details
Adalimumab biosimilar (Tonghua Dongbao Pharmaceutical) Phase 3 Clinical Tonghua Dongbao Pharmaceutical Co Ltd Arthritis, Rheumatoid; Psoriasis; Plaque psoriasis Details
Adalimumab biosimilar (Eastern Biotech) JY-026 Phase 1 Clinical Beijing Eastern Biotech Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Crohn Disease Details
Etanercept biosimilar (Suzhou Genemen Biotech) BF-02; GM-02 Phase 2 Clinical Suzhou Genemen Biotech. Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Details
Wogonin Phase 1 Clinical Shandong Buchang Pharmaceuticals Co Ltd, Hefei Cosource Medicine Technology, Daewoong Pharmaceutical Co Ltd, China Pharmaceutical University Respiratory Tract Infections; Neoplasms Details
Adalimumab biosimilar (Danhong Pharma) BC-002 Phase 3 Clinical Shandong Danhong Pharmaceutical Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Recombinant human monoclonal antibody specific for human tumor necrosis factor (North China Pharmaceutical) Phase 1 Clinical North China Pharmaceutical Company Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing; Autoimmune Diseases; Psoriasis Details
Recombinant human TNF-α monoclonal antibody (Sinocelltech) SCT-630 Phase 3 Clinical Shenzhou Cell Engineering Co Ltd Psoriasis; Plaque psoriasis Details
Tanfanercept HBM-9036; HL-036 Phase 3 Clinical Hanall Dry Eye Syndromes; Xerophthalmia Details
Hemay-005 Hemay-005 Phase 3 Clinical Hainan Hailing Chemipharma Corporation Ltd, Tianjin Hemay Pharmaceutical Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Behcet Syndrome; Dermatitis, Atopic; Plaque psoriasis Details
Orismilast LP-0058; LEO-32731 Phase 2 Clinical Leo Pharma Inc Drug-Related Side Effects and Adverse Reactions; Psoriasis; Dermatitis, Atopic Details
Golimumab biosimilar (Bio-thera) BAT-2506 Phase 3 Clinical Bio-Thera Solutions Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Arthritis Details
Adalimumab biosimilar (AXXO) Clinical Axxo Arthritis, Rheumatoid; Arthritis, Psoriatic Details
LY-3114062 LY3114062; LY-3114062 Phase 1 Clinical Eli Lilly And Company Arthritis Details
Hemay007 Hemay-007 Phase 2 Clinical Tianjin Hemay Bio-Tech Co Ltd Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Colitis, Ulcerative Details
Infliximab biosimilar (Ospedale San Raffaele) Phase 1 Clinical Ospedale San Raffaele Takayasu Arteritis Details
CD24-Fc MK-7110; MK7110; HAS-CD24; CD24-Fc-IgG; CD24-Fc Phase 3 Clinical Oncoimmune HIV Infections; Hematopoietic stem cell transplantation (HSCT); Leukemia; Graft vs Host Disease; Coronavirus Disease 2019 (COVID-19); Myelodysplastic Syndromes; Dyslipidemias; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Leukemia, Myeloid, Acute; Melanoma Details
Recombinant human anti-TNFα monoclonal antibody (Huaota Biopharma) Phase 3 Clinical Shanghai Huaao Tai Biopharma Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis; Plaque psoriasis Details
Monoclonal Antibody (Mab) sB24M Phase 1 Clinical Pyoderma Gangrenosum Details
Adalimumab biosimilar (Alphamab) KN-002 Phase 1 Clinical Suzhou Alphamab Co Ltd Arthritis, Rheumatoid; Asthma Details

This web search service is supported by Google Inc.

totop