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Your Position: Home > Receptor Tyrosine Kinases > EGF R > EGR-C5252

Rhesus macaque EGF R Protein, Fc Tag (MALS verified)

  • Synonym
    EGFR,ERBB,ERBB1,HER1,PIG61,mENA
  • Source
    Rhesus macaque EGF R, Fc Tag (EGR-C5252) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P55245).
    Predicted N-terminus: Leu 25
  • Molecular Characterization
    Online(Leu 25 - Ser 645) P55245

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 95.3 kDa. The protein migrates as 116-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Rhesus macaque EGF R, Fc Tag (Cat. No. EGR-C5252) SDS-PAGE gel

Rhesus macaque EGF R, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Rhesus macaque EGF R, Fc Tag (Cat. No. ) MALS images

The purity of Rhesus macaque EGF R, Fc Tag(Cat. No. EGR-C5252) was more than 85% and the molecular weight of this protein is around 225-245 kDa verified by SEC-MALS.

Bioactivity-ELISA
Rhesus macaque EGF R, Fc TagRhesus macaque EGF R, Fc Tag (Cat. No. EGR-C5252) ELISA bioactivity

Immobilized Human EGF, Tag Free at 10 μg/mL (100 μL/well) can bind Rhesus macaque EGF R, Fc Tag (Cat. No. EGR-C5252) with a linear range of 39-1250 ng/mL (QC tested).

  • Background
    The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $250.00

Price(USD) : $1440.00

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Drug Development Status

  • Number of Launched Drugs:30 Details
  • Number of Drugs in Clinical Trials:127 Details
  • Latest Research Phase:Approved

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