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Your Position: Home > Protein > Transferrin R2 > TF2-M5269

Mouse Transferrin R2 Protein, mouse IgG1 Fc Tag, low endotoxin

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  • Synonym
    Transferrin R2,TFR2
  • Source
    Mouse TFR2, Mouse Fc Tag(TF2-M5269) is expressed from human 293 cells (HEK293). It contains AA Arg 103 - Phe 798 (Accession # Q9JKX3-1).
    Predicted N-terminus: Val
  • Molecular Characterization
    Transferrin R2 Structure

    This protein carries a mouse IgG1 Fc tag at the N-terminus

    The protein has a calculated MW of 101.1 kDa. The protein migrates as 116 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 0.1 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Transferrin R2 SDS-PAGE

Mouse TFR2, Mouse Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • Background
    Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.
  • Clinical and Translational Updates

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Price(USD) : $350.00

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