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Product Details
Synonyms
FOLR-1, FBP, FOLR, FRα
Source
Cynomolgus / Rhesus macaque FOLR1, His Tag (FO1-C52H8) is expressed from human 293 cells (HEK293). It contains AA Arg 25 - Met 233 (Accession # NP_001181576.1). In the region Arg 25 - Met 233, the amino acid sequences of Cynomolgus and Rhesus macaque FOLR1 are identical.
Predicted N-terminus: Arg 25
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 26.4 kDa. The protein migrates as 32-41 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in Tris and Glycine, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Shipping and Storage
This product is shipped at ambient temperature.
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
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Performance Data
SDS-PAGE
Cynomolgus / Rhesus macaque FOLR1, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.
SEC-MALS
The purity of Cynomolgus / Rhesus macaque FOLR1, His Tag (Cat. No. FO1-C52H8) is more than 90% and the molecular weight of this protein is around 30-50 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA
Immobilized Folic acid-BSA conjugate at 5 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque FOLR1 Protein, His tag (Cat. No. FO1-C52H8) with a linear range of 8-32 ng/mL (QC tested).
Protocol
Immobilized Anti-FOLR1 Antibody,Mouse IgG1 at 1 μg/mL (100 μL/well) can bind Cynomolgus / Rhesus macaque FOLR1, His Tag (Cat. No. FO1-C52H8) with a linear range of 1-5 ng/mL (Routinely tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
Folate receptor alpha
- Category：
- Approved Drugs：
3 Details
- Drugs in Clinical Trials：
27 Details
- Highest Development Stage：
Approved
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