Human NTB-A / SLAMF6 Protein, His Tag (MALS verified)

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NTA-H52Ha-100ug
$340.00
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NTA-H52Ha-1mg
$2,140.00
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NTA-H52Ha
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Synonyms

NTB-A, SLAMF6, Ly108, NK-T-B-antigen, CD352, KALI

Source

Human NTB-A, His Tag (NTA-H52Ha) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Met 226 (Accession # Q96DU3-1).

Predicted N-terminus: Gln 22

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 25.0 kDa. The protein migrates as 35-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

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Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

Background

The SLAM family of receptors is composed of six members named SLAM (CD150); 2B4 (CD244); Ly-9 (CD229); CD84; natural killer, T and B cell antigen (NTB-A; Ly108 in the mouse. Most, if not all,immune cell types express more than one SLAM family receptor. All six SLAM-related genes are located within a 400–500 kilobase (kb) genomic segment on chromosome 1 in humans and mice. This feature implies that the genes that encode the SLAM family were created by serial gene duplication.