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Your Position: Home > All Other Proteins > IL-1 Rrp2 > Human IL-1 Rrp2 / IL-1 R6 Protein, Fc Tag

Human IL-1 Rrp2 / IL-1 R6 Protein, Fc Tag

  • Synonym
    IL-1 R6, IL-1 Rrp2, IL1RL2, IL-1RL2, IL1Rrp2, IL-1Rrp2, IL1RRP2, IL-36R
  • Source
    Human IL-1 Rrp2, Fc Tag (IL2-H5254) is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Arg 335 (Accession # Q9HB29-1).
    Predicted N-terminus: Asp 20
  • Molecular Characterization
    IL-1 Rrp2(Asp 20 - Arg 335) Q9HB29-1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 62.4 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arg, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    No activity loss was observed after storage at:

    1. 4-8°C for 12 months in lyophilized state;

    2. -70°C for 3 months under sterile conditions after reconstitution.

SDS-PAGE
Human IL-1 Rrp2, Fc Tag (Cat. No. IL2-H5254) SDS-PAGE gel

Human IL-1 Rrp2, Fc Tag on SDS-PAGE  under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
Human IL-1 Rrp2, Fc TagHuman IL-1 Rrp2, Fc Tag (Cat. No. IL2-H5254) ELISA bioactivity

Immobilized Recombinant Human IL-36Ra / IL-1F5 at 2 μg/mL (100 μL/well) can bind Human IL-1 Rrp2, Fc Tag (Cat. No. IL2-H5254) with a linear range of 0.156-5 μg/mL (QC tested).

  • Background
    The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9).  All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.
  • References
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $1980.00

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