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Your Position: Home > Immune Checkpoint Proteins > ICOS > ICS-M5259

Mouse ICOS / CD278 (C137S, C138S) Protein, Fc Tag

  • Synonym
    ICOS,CD278,AILIM,Inducible T-cell costimulator
  • Source
    Mouse ICOS (C137S, C138S), Fc Tag (ICS-M5259) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Leu 144 (Accession # Q9WVS0-1 (C137S, C138S)).
    Predicted N-terminus: Glu 21
  • Molecular Characterization
    Online(Glu 21 - Leu 144) Q9WVS0-1 (C137S, C138S)

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 40.6 kDa. The protein migrates as 45-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Mouse ICOS (C137S, C138S), Fc Tag (Cat. No. ICS-M5259) SDS-PAGE gel

Mouse ICOS (C137S, C138S), Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Bioactivity-ELISA
Mouse ICOS (C137S, C138S), Fc TagMouse ICOS (C137S, C138S), Fc Tag (Cat. No. ICS-M5259) ELISA bioactivity

Immobilized Human B7-H2, His Tag (Cat. No. B72-H5221) at 1 μg/mL (100 μL/well) can bind Mouse ICOS (C137S, C138S), Fc Tag (Cat. No. ICS-M5259) with a linear range of 0.3-10 ng/mL (QC tested).

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Price(USD) : $1980.00

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Drug Development Status

  • Number of Launched Drugs:0 Details
  • Number of Drugs in Clinical Trials:6 Details
  • Latest Research Phase:Phase ?

Datasheet & Documentation

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DMF (Drug Master File)

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