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Your Position: Home > All Other Proteins > BAFFR > BAR-H52H3

Human BAFFR / TNFRSF13C Protein, His Tag

  • Synonym
    BAFFR,TNFRSF13C,BROMIX,CD268,CVID4,prolixin,BAFF-R
  • Source
    Human BAFFR Protein, His Tag (BAR-H52H3) is expressed from human 293 cells (HEK293). It contains AA Ser 7 - Ala 71 (Accession # Q96RJ3-1).
  • Molecular Characterization
    Online(Ser 7 - Ala 71) Q96RJ3-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 8.6 kDa. The protein migrates as 13-20 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human BAFFR Protein, His Tag (Cat. No. BAR-H52H3) SDS-PAGE gel

Human BAFFR Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

Bioactivity-ELISA
Human BAFFR Protein, His TagHuman BAFFR Protein, His Tag (Cat. No. BAR-H52H3) ELISA bioactivity

Immobilized Human BAFF, Fc Tag, active trimer (Cat. No. BAF-H5261) at 1 μg/mL (100 μL/well) can bind Human BAFFR Protein, His Tag (Cat. No. BAR-H52H3) with a linear range of 1-10 ng/mL (QC tested).

Human BAFFR Protein, His TagHuman BAFFR Protein, His Tag (Cat. No. BAR-H52H3) ELISA bioactivity

Immobilized Human BAFFR Protein, His Tag (Cat. No. BAR-H52H3) at 2 μg/mL (100 μL/well) can bind Anti-BAFFR Antibody, Human IgG1 with a linear range of 0.1-5 ng/mL (Routinely tested).

Human BAFFR Protein, His TagHuman BAFFR Protein, His Tag (Cat. No. BAR-H52H3) ELISA bioactivity

Immobilized Biotinylated Human BAFF, His,Avitag (active trimer) (MALS verified) (Cat. No. BAF-H82Q2) at 1 μg/mL (100 μL/well) on Recombinant Streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate, can bind Human BAFFR Protein, His Tag (Cat. No. BAR-H52H3) with a linear range of 0.3-2 ng/mL (Routinely tested).

Human BAFFR Protein, His TagHuman BAFFR Protein, His Tag (Cat. No. BAR-H52H3) ELISA bioactivity

Serial dilutions of Anti-BAFFR Antibody, Human IgG1 were added into Human BAFFR, Fc Tag (Cat. No. BAR-H5257) : Biotinylated Human BAFF, His,Avitag (active trimer) (MALS verified) (Cat. No. BAF-H82Q2) binding reactions. The half maximal inhibitory concentration (IC50) is 1.7056 μg/mL (Routinely tested).

  • Background
    BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.
  • References
    • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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    Order Details

    Price(USD) : $350.00

    Price(USD) : $2310.00

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