Anti-SARS-CoV-2 Spike RBD Neutralizing Antibody, Chimeric mAb, Human IgG1 (AM122) (Trehalose free)

Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) is a chimeric monoclonal antibody recombinantly expressed in HEK293 cells, which combines the variable regions of a mouse monoclonal antibody with human IgG1 constant domains. The mouse monoclonal antibody was obtained from a mouse immunized with recombinant SARS-CoV-2 Spike S1 protein. As verified in competitive ELISA-based and pseudovirus-based neutralization assay, this chimeric monoclonal can potently neutralize all SARS-CoV-2 Variants of Concern (VOCs), including Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1) and Delta (B.1.617.2).

Recombinant Monoclonal

AM122

Human IgG1, Kappa

Mouse

Virus

This product is a specific antibody against SARS-CoV-2 Spike protein RBD domain. No cross-reactivity is detected with Spike protein RBD domain of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

Protein A purified.

Less than 10%, as determined by SEC-MALS.

Please refer to the Certificate of Analysis (CoA).

Liquid

Supplied a 0.22 μm-filtered solution in PBS (pH 7.4).

Please contact us for customized product forms or formulations.

Please avoid repeated freeze-thaw cycles.

• For long term storage, the product is stable for up to 3 years at -70°C from date of receipt;
• For short term storage, the product is stable for up to 12 months at 2-8°C from date of receipt.

Product Specific Notices: For research use only.