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Your Position: Home > Viral Proteins > Nucleocapsid protein > NUN-V5146

HCoV-NL63 Nucleocapsid protein, His Tag

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  • Synonym
    Nucleocapsid protein,NP,Protein N,COVID-19
  • Source
    HCoV-NL63 Nucleocapsid, His Tag (NUN-V5146) is expressed from E.coli cells. It contains AA Met 1 - His 377 (Accession # Q6Q1R8-1).
    Predicted N-terminus: His
  • Molecular Characterization
    Online-Res(Met 1 - His 377) Q6Q1R8-1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 44 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
  • References
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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