Onchocerca volvulus OV16 protein, GST Tag

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OV6-V51G4-100ug
$360.00
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OV6-V51G4-1mg (500ug X 2)
$2,615.00
OV6-V51G4
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Synonyms

OV16 (Onchocerca volvulus)

Source

Onchocerca volvulus OV16, GST Tag (OV6-V51G4) is expressed from E. coli cells. It contains AA Lys 17 - Asp 197 (Accession # P31729-1).

Predicted N-terminus: Met

Molecular Characterization

This protein carries a GST tag at the N-terminus.

The protein has a calculated MW of 46.8 kDa. The protein migrates as 45 kDa under reducing (R) condition (SDS-PAGE).

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

Background

The OV16 antigen, localizes to the hypodermis, cuticle, and uterus of female O. volvulus is regarded as a highly sensitive and specific antigen for detection of IgG4 in people with prior exposure to onchocerciasis. It has an open reading frame that encodes a 152- amino acid polypeptide containing a 16-amino acid putative signal peptide. Enzyme-linked Immunosorbent Assay serological testing of OV-16 antigen is a diagnostic tool for determining effective elimination of the parasite.