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Product Details
Synonyms
ACE-2, ACEH, ACE2
Source
Human ACE2, His Tag (AC2-H52H4) is expressed from human 293 cells (HEK293).
Request for sequenceMolecular Characterization
This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 85.5 kDa. The protein migrates as 90-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
Formulation
Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Shipping and Storage
This product is supplied and shipped on dry ice.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- The product MUST be stored at -70°C or lower upon receipt;
- -70°C for 3 months under sterile conditions.
ACRO Quality Management System
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Performance Data
SDS-PAGE
Human ACE2, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS
The purity of Human ACE2, His Tag (Cat. No. AC2-H52H4) is more than 85% and the molecular weight of this protein is around 170-220 kDa verified by SEC-MALS.
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Bioactivity-ELISA
Immobilized Human ACE2, His Tag (Cat. No. AC2-H52H4) at 2 μg/mL (100 μL/well) can bind SARS-CoV-2 S protein RBD, Fc Tag (Cat. No. SPD-C5255) with a linear range of 0.1-0.8 ng/mL (QC tested).
Protocol
Immobilized Human ACE2, His Tag (Cat. No. AC2-H52H4) at 2 μg/mL (100 μL/well) can bind SARS-CoV-2 S1 protein, Fc Tag (Cat. No. S1N-C5255) with a linear range of 0.4-6 ng/mL (Routinely tested).
Protocol
Immobilized SARS-CoV-2 S protein RBD, Fc Tag (Cat. No. SPD-C5255) at 2 μg/mL (100 μL/well) can bind Human ACE2, His Tag (Cat. No. AC2-H52H4) with a linear range of 0.02-0.16 μg/mL (Routinely tested).
Protocol
Immobilized SARS-CoV-2 S1 protein, Fc Tag (Cat. No. S1N-C5255) at 2 μg/mL (100 μL/well) can bind Human ACE2, His Tag (Cat. No. AC2-H52H4) with a linear range of 39-156 ng/mL (Routinely tested).
Protocol
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Background
Recent Advances
Drug Development Progress- English Name：
Angiotensin-converting enzyme 2
- Category：
- Approved Drugs：
0 Details
- Drugs in Clinical Trials：
7 Details
- Highest Development Stage：
Phase 2 Clinical
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