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Your Position: Home > All Other Proteins > CEACAM-5 > CE5-M5253

Mouse CEACAM-5 Protein, Fc Tag

  • Synonym
    CEACAM-5,CD66e,CEA,Meconium antigen 100
  • Source
    Mouse CEACAM-5, Fc Tag (CE5-M5253) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Glu 947 (Accession # Q3UKK2-1).
  • Molecular Characterization
    Online(Gln 35 - Glu 947) Q3UKK2-1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 129.2 kDa. The protein migrates as 135-180 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Mouse CEACAM-5, Fc Tag (Cat. No. CE5-M5253) SDS-PAGE gel

Mouse CEACAM-5, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

  • Background
    Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $300.00

Price(USD) : $1980.00

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  • Latest Research Phase:Phase 3 Clinical

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