Biotinylated Human CD7 Protein, Fc,Avitag™ (MALS verified)

Cat. No. / Size
Price
Qty
CD7-H82F3-25ug
$360.00
CD7-H82F3-200ug
$1565.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    CD7, GP40, TP41, LEU-9, Tp40

  • Source

    Biotinylated Human CD7, Fc,Avitag (CD7-H82F3) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Pro 180 (Accession # P09564-1).

    Predicted N-terminus: Ala 26

    Request for sequence
  • Molecular Characterization

    CD7 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™).

    The protein has a calculated MW of 44.6 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Labeling

    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.

  • Protein Ratio

    Passed as determined by the HABA assay / binding ELISA.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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Performance Data

  • SDS-PAGE

    CD7 SDS-PAGE

    Biotinylated Human CD7, Fc,Avitag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

  • SEC-MALS

    CD7 SEC-MALS

    The purity of Biotinylated Human CD7, Fc,Avitag (Cat. No. CD7-H82F3) is more than 95% and the molecular weight of this protein is around 95-115 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     CD7 ELISA

    Immobilized Biotinylated Human CD7, Fc,Avitag (Cat. No. CD7-H82F3) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Anti-CD7 antibody, Mouse IgG1 with a linear range of 0.2-2 ng/mL (QC tested).

    Protocol

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Background

T-cell antigen CD7 (CD7) is also known as GP40, LEU-9, TP41 and Tp40. CD7 is a protein that in humans is encoded by the CD7 gene, this gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. CD7 has been shown to interact with PIK3R1. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.

Recent Advances

 
Drug Development Progress
  • English Name:

    T-cell antigen CD7

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    32 Details

  • Highest Development Stage:

    Phase 2 Clinical

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