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Your Position: Home > All Other Proteins > IL-2 R alpha > ILA-C52H4

Canine IL-2 R alpha / CD25 Protein, His Tag

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  • Synonym
    IL2RA,CD25,p55,IL2-RA,IL-2-RA
  • Source
    Canine IL-2 R alpha, His Tag (ILA-C52H4) is expressed from human 293 cells (HEK293). It contains AA Asp 22 - Gln 237 (Accession # O62802-1).
    Predicted N-terminus: Asp 22
  • Molecular Characterization
    Online-Res(Asp 22 - Gln 237) O62802-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 26.4 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Interleukin-2 receptor subunit alpha (IL2RA) is also known as IL-2R subunit alpha, IL-2-RA, IL2-RA, TAC antigen, p55, CD antigen CD25, is a type I transmembrane glycoprotein. IL2RA is expressed on activated T cells and regulatory T cells, and is capable of binding IL2 with low affinity by itself. However, a ligand-induced high affinity heterotrimeric receptor complex is produced when IL2RA is associated non-covelently with the IL2 receptor beta and gamma chain, and subsequently initiates the intacellular signal pathways such as MAPK or JAK/STAT. On dendritic cells (DC), CD25 has been previously regarded as an activation marker, while both murine and human DC can express CD25, they do not express the beta-chain of the IL-2 receptor, which is indispensable for the execution of IL-2 signaling.
  • References
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $300.00

Price(USD) : $1980.00

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  • Latest Research Phase:Approved

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