0
There is no goods in the shopping cart !
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9
Your Position: Home > All Other Proteins > Cadherin-6 > CA6-H5258

Human Cadherin-6 / KCAD / CDH6 Protein, Fc Tag (MALS verified)

  • Synonym
    CDH6,CAD6,KCAD,K-cadherin,Cadherin-6
  • Source
    Human Cadherin-6 Protein, Fc Tag (CA6-H5258) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Ala 615 (Accession # P55285-1).
    Predicted N-terminus: Thr 19
  • Molecular Characterization
    Online(Thr 19 - Ala 615) P55285-1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 92.8 kDa. The protein migrates as 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human Cadherin-6 Protein, Fc Tag (Cat. No. CA6-H5258) SDS-PAGE gel

Human Cadherin-6 Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.

SEC-MALS
Human Cadherin-6 Protein, Fc Tag (Cat. No. ) MALS images

The purity of Human Cadherin-6 Protein, Fc Tag (Cat. No. CA6-H5258) was more than 90% and the molecular weight of this protein is around 200-240 kDa verified by SEC-MALS.

Bioactivity-ELISA
Human Cadherin-6 Protein, Fc TagHuman Cadherin-6 Protein, Fc Tag (Cat. No. CA6-H5258) ELISA bioactivity

Immobilized Human Cadherin-6 Protein, Fc Tag (Cat. No. CA6-H5258) at 1 μg/mL (100 μL/well) can bind Human Cadherin-6 Antibody, Mouse IgG1 with a linear range of 0.1-1 ng/mL (QC tested).

  • Background
    Cadherin-6 (CDH6) is also known as Kidney cadherin (K-cadherin or KCAD), is a a type II classical cadherin from the cadherin superfamily. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH6 / KCAD contains five cadherin domains. CDH6 is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression and also expressed in certain liver and kidney carcinomas.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

Comments (0)

Order Details

Price(USD) : $290.00

Price(USD) : $1800.00

Promotion & Exhibitions



Datasheet & Documentation

Request for DMF
DMF (Drug Master File)

Contact Us

+1  800-810-0816 (US)
+86 400-682-2521 (AP)

Questions & Comments

This web search service is supported by Google Inc.

totop