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Your Position: Home > All Other Proteins > CD37 > CD7-H525a

Human CD37 Protein, Fc Tag (MALS verified)

  • Synonym
    CD37,Tspan-26,TSPAN26
  • Source
    Human CD37, Fc Tag (CD7-H525a) is expressed from human 293 cells (HEK293). It contains AA Arg 112 - Asn 241 (Accession # P11049-1).
    Predicted N-terminus: Arg 112
  • Molecular Characterization
    Online(Arg 112 - Asn 241) P11049-1

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 41.3 kDa. The protein migrates as 50-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human CD37, Fc Tag (Cat. No. CD7-H525a) SDS-PAGE gel

Human CD37, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Human CD37, Fc Tag (Cat. No. ) MALS images

The purity of Human CD37, Fc Tag (Cat. No. CD7-H525a) was more than 90% and the molecular weight of this protein is around 95-105 kDa verified by SEC-MALS.

  • Background
    Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $350.00

Price(USD) : $2310.00

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  • Number of Drugs in Clinical Trials:7 Details
  • Latest Research Phase:Phase 2 Clinical

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