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Your Position: Home > Cytokines > IL-17A > ILA-C52H7

Canine IL-17A / CTLA-8 Protein, His Tag

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  • Synonym
    IL-17A,Interleukin-17A,CTLA-8,IL-17
  • Source
    Canine IL-17A, His Tag (ILA-C52H7) is expressed from human 293 cells (HEK293). It contains AA Gly 26 - Ala 155 (Accession # NP_001159350.1).
    Predicted N-terminus: His
  • Molecular Characterization
    Online-Res(Gly 26 - Ala 155) NP_001159350.1

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 17.0 kDa.

  • Endotoxin
  • Formulation

    Please contact us for detailed information.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Background
    Interleukin-17A (IL17A) is also known as cytotoxic T-lymphocyte-associated antigen 8 (CTLA8),which is a proinflammatory cytokine produced by activated T cells. IL17A can regulate the activities of NF-kappaB and mitogen-activated protein kinases. Also,IL17A can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO).Furthermore,IL17A has been found both in glycosylated and nonglycosylated forms. High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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Price(USD) : $380.00

Price(USD) : $2540.00

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Drug Development Status

  • Number of Launched Drugs:3 Details
  • Number of Drugs in Clinical Trials:13 Details
  • Latest Research Phase:Approved

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