Product Details
Synonyms
TNFRSF9, 4-1BB, CD137, CDw137, ILA
Source
Canine 4-1BB Protein, Fc Tag (41B-C5253) is expressed from human 293 cells (HEK293). It contains AA Ile 24 - Ser 185 (Accession # XP_850336.1).
Predicted N-terminus: Ile 24
Request for sequenceMolecular Characterization

Other Tags and Version Biotin & Other Labeled Version
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 43.4 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>95% as determined by SEC-MALS.
Formulation
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
Customers Also Viewed
Performance Data
SDS-PAGE

Canine 4-1BB Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-MALS

The purity of Canine 4-1BB Protein, Fc Tag (Cat. No. 41B-C5253) is more than 95% and the molecular weight of this protein is around 95-110 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Human 4-1BB Ligand, Mouse IgG2a Fc Tag, low endotoxin at 5 μg/mL (100 μL/well) can bind Canine 4-1BB Protein, Fc Tag (Cat. No. 41B-C5253) with a linear range of 0.3-5 ng/mL (QC tested).
Protocol
Customer Reviews Writing Reviews

Background
Recent Advances
- English Name:
Tumor necrosis factor receptor superfamily member 9
- Category:
- Approved Drugs:
0 Details
- Drugs in Clinical Trials:
77 Details
- Highest Development Stage:
Phase 3 Clinical
[North America]: +1 800-810-0816
[Switzerland]: +41 800 040 012
[Asia & Pacific]: +86 400-682-2521



















