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Your Position: Home > Protein > BTN2A1 > BT1-H52H6

Human BTN2A1 / Butyrophilin Protein, His Tag (MALS verified)

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  • Synonym
    BK14H9.1,BT2.1,BTF1,BTF1BT2.1butyrophilin BTF1,BTN2A1,butyrophilin subfamily 2 member A1,butyrophilin,subfamily 2,member A1,DJ3E1.1,FLJ36567
  • Source
    Human BTN2A1 Protein, His Tag (BT1-H52H6) is expressed from human 293 cells (HEK293). It contains AA Gln 29 - Ala 248 (Accession # Q7KYR7-2).
    Predicted N-terminus: Gln 29
  • Molecular Characterization

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 26.4 kDa. The protein migrates as 38-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
Human BTN2A1 Protein, His Tag (Cat. No. BT1-H52H6) SDS-PAGE gel

Human BTN2A1 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95%.

Human BTN2A1 Protein, His Tag (Cat. No. ) MALS images

The purity of Human BTN2A1 Protein, His Tag (Cat. No. BT1-H52H6) is more than 90% and the molecular weight of this protein is around 30-46kDa verified by SEC-MALS.

  • Background
    Duplication events have led to three paralogues of BTN2A in primates: BTN2A1, BTN2A2, and BTN2A3. In humans, only BTN2A1 has been functionally characterised; it has been detected on epithelial cells and leukocytes, and identified as a novel ligand of dendritic cell-specific ICAM-3 grabbing nonintegrin (DCSIGN), a C-type lectin receptor that acts as an internalization receptor for HIV-1, HCV, and other pathogens. BTN2A2 mRNA has been shown to be expressed in circulating human immune cells.
  • Clinical and Translational Updates
  • Please contact us via if you have any question on this product.

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Price(USD) : $350.00

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