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Your Position: Home > CAR-T > CD171 > CD1-H52H4

Human CD171 Protein, His Tag (MALS verified)

  • Synonym
    CD171/L1CAM
  • Source
    Human CD171, His Tag (CD1-H52H4) is expressed from human 293 cells (HEK293). It contains AA Ile 20 - Glu 1120 (Accession # P32004-1).
    Predicted N-terminus: Ile 20
  • Molecular Characterization
    Online(Ile 20 - Glu 1120) P32004-1

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 125.1 kDa. The protein migrates as 160-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin
    Less than 1.0 EU per μg by the LAL method.
  • Purity

    >95% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH8.0. Normally trehalose is added as protectant before lyophilization.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
SDS-PAGE
Human CD171, His Tag (Cat. No. CD1-H52H4) SDS-PAGE gel

Human CD171, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

SEC-MALS
Human CD171, His Tag (Cat. No. ) MALS images

The purity of Human CD171, His Tag (Cat. No. CD1-H52H4) is more than 90% and the molecular weight of this protein is around 208-248 kDa verified by SEC-MALS.

  • Background
    L1CAM is a cell adhesion molecule of the immunoglobulin superfamily which was originally discovered as a major player in the development of the nervous system. L1CAM was demonstrated to have prognostic value in different cancers and to be a promising target for anti-cancer therapy.
  • Clinical and Translational Updates
      
  • Please contact us via TechSupport@acrobiosystems.com if you have any question on this product.

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